Protein detail

SMCO3

Single-pass membrane and coiled-coil domain-containing protein 3

Protein symbol
SMCO3
UniProt ID
EVMP score
0.50
Frequency
5
Transmembrane count
1
Protein classification
Predicted membrane proteins
Basic Information
Protein Names
Single-pass membrane and coiled-coil domain-containing protein 3
Protein Class
Predicted membrane proteins
Transmembrane
155..175; Helical
Transmembrane Count
1
Entrez Gene Symbol
Gene Synonym
C12orf69LOC440087
Gene Description
Single-pass membrane protein with coiled-coil domains 3
Chromosome
12
Position
14804650-14814182
Frequency
5
EVMP Score
0.50
Fluorescence & Localization
Cell SpecificEndometrial ciliated cells
Function & Pathway
Cellular Component
Molecular Function
Canonical Pathways
  • M134 Pid tcr ras pathway
  • M270 Pid mapk trk pathway
  • M281 Pid fak pathway
Mediation Categories
Other mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

6 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
transmembranetransmembraneUniProt_locationNoNoNoNoNo
transmembranetransmembraneUniProt_topologyNoNoNoNoNo
transmembranetransmembraneUniProt_keywordNoNoNoNoNo
transmembranetransmembraneRamilowski_locationNoNoNoNoNo
transmembranetransmembraneOmniPathNoNoNoNoNo
transmembrane_tmhmmtransmembrane_predictedAlmen2009NoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationWestern BlottingMass SpectrometryFlow Cytometry138207106
Sequence, Structure & Domains

Sequences

Length
225
Mass
24,877
Sequence
MAQSDFLYPENPKRREEVNRLHQQLLDCLSDSFDVTNKLTEVLNMHLGCRLASIEMKRDGTIKENCDLIIQAIMKIQKELQKVDEALKDKLEPTLYRKLQDIKEKETDKIAIVQKVISVILGEATSAASAVAVKLVGSNVTTGIINKLVTVLAQIGASLLGSIGVAVLGLGIDMIVRAILGAVEKTQLQAAIKSYEKHLVEFKSASEKYNHAITEVINTVKHQMK

3D Structural Models

Domain & Motif Annotations

Coiled Coil
62..92; 183..207
Clinical Relevance