Protein detail

CC154

Coiled-coil domain-containing protein 154

Entry name
CC154
UniProt ID
EVMP confidence score
0.38
Supporting publications (n)
1
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information11
Protein Names
Coiled-coil domain-containing protein 154
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym (2)
C16orf29LOC645811
Gene Description
Coiled-coil domain containing 154
Chromosome
16
Position
1434383-1444556
Supporting publications (n)
1
EVMP confidence score
0.38
Fluorescence & Localization6
Tissue SpecificesophagusBrain Regional Specificchoroid plexusCell SpecificBreast lactating cellsSingle-Nuclei Brain Specificchoroid plexus epithelial cellBlood Cell SpecificgdT-cellBlood Lineage SpecificT-cells
Function & Pathway4
Relations & Evidence5

Ligand-Receptor Signaling (4)

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyMass spectrometry23614683438207106
Sequence, Structure & Domains4

Sequences

Length
667
Mass
75,408
Sequence
MSELADSGPSGASAPSQLRAVTLEDLGLLLAGGLASPEPLSLEELSERYESSHPTSTASVPEQDTAKHWNQLEQWVVELQAEVACLREHKQRCERATRSLLRELLQVRARVQLQGSELRQLQQEARPAAQAPEKEAPEFSGLQNQMQALDKRLVEVREALTRLRRRQVQQEAERRGAEQEAGLRLAKLTDLLQQEEQGREVACGALQKNQEDSSRRVDLEVARMQAQVTKLGEEVSLRFLKREAKLCGFLQKSFLALEKRMKASESSRLKLEGSLRGELESRWEKLRGLMEERLRALQGQHEESHLLEQCQGLDAAVAQLTKFVQQNQASLNRVLLAEEKAWDAKGRLEESRAGELAAYVQENLEAAQLAGELARQEMHGELVLLREKSRALEASVAQLAGQLKELSGHLPALSSRLDLQEQMLGLRLSEAKTEWEGAERKSLEDLARWRKEVTEHLRGVREKVDGLPQQIESVSDKCLLHKSDSDLRISAEGKAREFKVGALRQELATLLSSVQLLKEDNPGRKIAEMQGKLATFQNQIMKLENCVQANKTIQNLRFNTEARLRTQEMATLWESVLRLWSEEGPRTPLGSWKALPSLVRPRVFIKDMAPGKVVPMNCWGVYQAVRWLRWKASLIKLRALRRPGGVLEKPHSQEQVQQLTPSLFIQK

Domain & Motif Annotations

Coiled Coil
76..182; 215..302; 384..410; 457..521
Clinical Relevance1
Supporting Publications1
PMIDTitleAbstract
32384937Alzheimer's disease progression characterized by alterations in the molecular profiles and biogenesis of brain extracellular vesicles.No abstract available