Protein detail

CCD69

Coiled-coil domain-containing protein 69

Entry name CCD69	UniProt ID A6NI79	EVMP score 0.38
Frequency 2	Transmembrane count	Protein classification Predicted intracellular proteins

EVMP score: annotation confidence score.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information

Protein Names

Coiled-coil domain-containing protein 69

Protein Class

Predicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000198624

Entrez Gene Symbol

CCDC69

Gene Synonym

DKFZP434C171FLJ13705

Gene Description

Coiled-coil domain containing 69

Chromosome

Position

151181052-151224093

Frequency

EVMP Score

0.38

Fluorescence & Localization

Function & Pathway

Protein Function

Predicted intracellular proteins

Cellular Component

Molecular Function

GO:0008017 microtubule binding

Biological Process

Mediation Categories

Other mediation

Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	UniProt_location	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Regulatory Interaction Network

0 records.

Protein Complex Composition

2 records.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
	CCDC69 NAA10 RMI1 RMI2 TOP3A	A6NI79 P41227 Q13472 Q96E14 Q9H9A7	0:0:0:0:0	hu.MAP2
	CCDC69 RMI1 RMI2 TOP3A	A6NI79 Q13472 Q96E14 Q9H9A7	0:0:0:0	hu.MAP2

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity Capture	Mass spectrometry	6	40189497 38113368 33592500 32560723 36146834 38207106

Sequence, Structure & Domains

Sequences

Length

296

Mass

34,796

Sequence

MGCRHSRLSSCKPPKKKRQEPEPEQPPRPEPHELGPLNGDTAITVQLCASEEAERHQKDITRILQQHEEEKKKWAQQVEKERELELRDRLDEQQRVLEGKNEEALQVLRASYEQEKEALTHSFREASSTQQETIDRLTSQLEAFQAKMKRVEESILSRNYKKHIQDYGSPSQFWEQELESLHFVIEMKNERIHELDRRLILMETVKEKNLILEEKITTLQQENEDLHVRSRNQVVLSRQLSEDLLLTREALEKEVQLRRQLQQEKEELLYRVLGANASPAFPLAPVTPTEVSFLAT

3D Structural Models

Domain & Motif Annotations

Compositional Bias

1..18; Basic residues; 19..33; Basic and acidic residues

Coiled Coil

48..272

Region

1..41; Disordered

Protein Families

CCDC69 family

Sequence Similarities

Belongs to the CCDC69 family.

Clinical Relevance

Antibody

HPA043648 HPA052896