Protein detail
LRIQ3
Leucine-rich repeat and IQ domain-containing protein 3 (Leucine-rich repeat-containing protein 44)
Protein symbol LRIQ3 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Leucine-rich repeat and IQ domain-containing protein 3 (Leucine-rich repeat-containing protein 44)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
LRRC44MGC22773
Gene Description
Leucine rich repeats and IQ motif containing 3
Chromosome
1
Position
74026015-74198187
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificliverCell SpecificHepatocytesSingle-Nuclei Brain Specificependymal cell
Function & Pathway
Protein Function
Predicted intracellular proteins
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
2 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationDensity Gradient CentrifugationImmunoaffinity Capture | Western blottingMass spectrometry | 1 | 36189227 |
Sequence, Structure & Domains
Sequences
Length
624
Mass
73,675
Sequence
MFHGTVTEELTSHEEWSHYNENIREGQKDFVFVKFNGLHLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNGLKNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWHLPERFKACNHRLFFNFCPALRKGTTYEEEINNIKHITSKINAILAHNSPVLIVQRWIRGFLVRKNLSPVFFHKKKQQEKIIRGYEAKWIYITKGYEDKLLKDLFFKPETNIKGKLAYWKHNIYYPVDLKNSSEHRKHVSSILCELKPKDLGMKSKTSRHLIQKGQESEDEIVDEKLDTSFRISVFKLPIYTSGSLKNNAVLREKKQHFFPAYPQPIYTTHPKPIIKKDIRLERSMKEFFAPQRAGMKLRTFSDIDKYYTEQKKQEYHKEKVRVVAMAQVARERVRVAVNEHLNQKKYATQKLIEENKETIQNSLRQVWQNRFNYLEKARERKALFLKEKSQKASERLLVQNLNNERTLLTRGLLKIDRLEKNEAVLKEKSLIVKQKLKAEKYRKNLLKEMKKVRSQEIYKRHCEEKFVMDMIAFEKACERLQDAKTKVAIVKTNLDFKVPNGLIK
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=A6PVS8-1; Sequence=Displayed; Name=2; IsoId=A6PVS8-2; Sequence=VSP_029410, VSP_029411; Name=3; IsoId=A6PVS8-3; Sequence=VSP_029408, VSP_029409
Alternative Sequence
192..199; GTTYEEEI -> EKMKHSEV (in isoform 3); 200..624; Missing (in isoform 3); 290..299; NIYYPVDLKN -> DKKKLWVNFH (in isoform 2); 300..624; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Repeat
51..72; LRR 1; 73..94; LRR 2; 98..119; LRR 3
Coiled Coil
553..614
Domain (FT)
132..179; LRRCT; 215..244; IQ
Clinical Relevance
Antibody