Protein detail

P20L1

PHD finger protein 20-like protein 1

Protein symbol P20L1	UniProt ID A8MW92	EVMP score 0.38
Frequency 1	Transmembrane count	Protein classification Predicted intracellular proteins

EVMP score: annotation confidence score.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information

Protein Names

PHD finger protein 20-like protein 1

Protein Class

Predicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000129292

Entrez Gene Symbol

PHF20L1

Gene Synonym

CGI-72FLJ13649FLJ21615MGC64923TDRD20B

Gene Description

PHD finger protein 20 like 1

Chromosome

Position

132775358-132848807

Frequency

EVMP Score

0.38

Fluorescence & Localization

Tissue Specifictongue

Function & Pathway

Protein Function

Predicted intracellular proteins

Cellular Component

Molecular Function

Biological Process

Reactome

Canonical Pathways

M56 Pid lpa4 pathway
M8 Pid endothelin pathway
M15 Pid lysophospholipid pathway

Mediation Categories

Other mediation

Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	UniProt_location	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Regulatory Interaction Network

0 records.

Protein Complex Composition

3 records.

Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs
PHF20L1	A8MW92	2	PDB	PDB:6l1pPDB:6l0xPDB:6l10
ADIPOR1 CHRAC1 DR1 HCFC1 KAT2A MOCS2 PHF20L1 POLE3 POLE4 REEP4 SGF29 WDR5 YEATS2	A8MW92 O96007 P51610 P61964 Q01658 Q92830 Q96A54 Q96ES7 Q9H6H4 Q9NR33 Q9NRF9 Q9NRG0 Q9ULM3	1:1:1:1:1:1:1:1:1:1:1:1:1	NetworkBlastCompleat	Compleat:HC9317
DNMT1 PHF20L1	A8MW92 P26358	1:1	PDB	PDB:6l1f

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity Capture	Western blottingELISA	3	38731868 26775013 40098346

Sequence, Structure & Domains

Sequences

Length

1,017

Mass

115,010

Sequence

MSKKPPNRPGITFEIGARLEALDYLQKWYPSRIEKIDYEEGKMLVHFERWSHRYDEWIYWDSNRLRPLERPALRKEGLKDEEDFFDFKAGEEVLARWTDCRYYPAKIEAINKEGTFTVQFYDGVIRCLKRMHIKAMPEDAKGQVKSQHPLSWCCPIDPAGSCNQSMGSEDWIALVKAAAAAAAKNKTGSKPRTSANSNKDKDKDERKWFKVPSKKEETSTCIATPDVEKKEDLPTSSETFGLHVENVPKMVFPQPESTLSNKRKNNQGNSFQAKRARLNKITGLLASKAVGVDGAEKKEDYNETAPMLEQAISPKPQSQKKNEADISSSANTQKPALLSSTLSSGKARSKKCKHESGDSSGCIKPPKSPLSPELIQVEDLTLVSQLSSSVINKTSPPQPVNPPRPFKHSERRRRSQRLATLPMPDDSVEKVSSPSPATDGKVFSISSQNQQESSVPEVPDVAHLPLEKLGPCLPLDLSRGSEVTAPVASDSSYRNECPRAEKEDTQMLPNPSSKAIADGRGAPAAAGISKTEKKVKLEDKSSTAFGKRKEKDKERREKRDKDHYRPKQKKKKKKKKKSKQHDYSDYEDSSLEFLERCSSPLTRSSGSSLASRSMFTEKTTTYQYPRAILSVDLSGENLSDVDFLDDSSTESLLLSGDEYNQDFDSTNFEESQDEDDALNEIVRCICEMDEENGFMIQCEECLCWQHSVCMGLLEESIPEQYICYICRDPPGQRWSAKYRYDKEWLNNGRMCGLSFFKENYSHLNAKKIVSTHHLLADVYGVTEVLHGLQLKIGILKNKHHPDLHLWACSGKRKDQDQIIAGVEKKIAQDTVNREEKKYVQNHKEPPRLPLKMEGTYITSEHSYQKPQSFGQDCKSLADPGSSDDDDVSSLEEEQEFHMRSKNSLQYSAKEHGMPEKNPAEGNTVFVYNDKKGTEDPGDSHLQWQLNLLTHIENVQNEVTSRMDLIEKEVDVLESWLDFTGELEPPDPLARLPQLKRHIKQLLIDMGKVQQIATLCSV

Alternative Products

Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=A8MW92-1; Sequence=Displayed; Name=2; IsoId=A8MW92-2; Sequence=VSP_033781, VSP_033782, VSP_033783; Name=4; IsoId=A8MW92-4; Sequence=VSP_040407, VSP_040408

Alternative Sequence

144..169; Missing (in isoform 2); 311; A -> V (in isoform 2); 312..1017; Missing (in isoform 2); 547..573; KRKEKDKERREKRDKDHYRPKQKKKKK -> IRSWDFSALLMKIPSYSPISLSGLPES (in isoform 4); 574..1017; Missing (in isoform 4)

3D Structural Models

Turn

24..26; 38..41; 60..62

Helix

52..54; 130..132; 138..140

Beta Strand

18..22; 28..37; 42..47; 56..59; 63..67; 92..96; 98..111; 114..120; 125..128

3D Structure

NMR spectroscopy (3); X-ray crystallography (6)

Domain & Motif Annotations

Compositional Bias

186..197; Polar residues; 198..218; Basic and acidic residues; 315..346; Polar residues; 405..416; Basic residues; 444..454; Polar residues; 496..505; Basic and acidic residues; 515..527; Low complexity; 530..565; Basic and acidic residues; 566..579; Basic residues; 881..894; Acidic residues; 908..918; Basic and acidic residues

Zinc Finger

681..729; PHD-type

Domain (FT)

11..71; Tudor 1; 85..141; Tudor 2

Region

183..248; Disordered; 307..371; Disordered; 389..458; Disordered; 473..585; Disordered; 862..923; Disordered

Clinical Relevance

Antibody

HPA025060 HPA028417

Interaction Protein

ENSG00000120071ENSG00000139620

Interaction Count

Interaction Dataset

biogrid_bioplex