Protein detail

BTBDI

BTB/POZ domain-containing protein 18

Entry name BTBDI	UniProt ID B2RXH4	EVMP confidence score 0.38
Supporting publications (n) 1	Transmembrane count	Protein classification Predicted intracellular proteins

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information10

Protein Names

BTB/POZ domain-containing protein 18

Protein Class

Predicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000233436

Entrez Gene Symbol

BTBD18

Gene Description

BTB domain containing 18

Chromosome

Position

57743514-57752675

Supporting publications (n)

EVMP confidence score

0.38

Fluorescence & Localization5

Tissue Specificadipose tissueCell SpecificAdipocytesSingle-Nuclei Brain Specificcommitted oligodendrocyte precursorBlood Cell Specificclassical monocyteBlood Lineage Specificdendritic cells

Function & Pathway5

Protein Function

Predicted intracellular proteins

Cellular Component

GO:0005634 nucleus

Molecular Function

GO:0005515 protein binding

Biological Process (3)

Mediation Categories

Other mediation

Relations & Evidence5

Ligand-Receptor Signaling (4)

4 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	UniProt_location	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential Ultracentrifugation	Mass spectrometryWestern blottingMORPH	2	38731868 39835386

Sequence, Structure & Domains6

Sequences

Length

712

Mass

77,931

Sequence

MCSPASPKILYRNPRFLRLAFLQLHHQQQSDVFCDVLLQAEGEAVPAHCCILSACSPFFTERLERERPAQGGKVVLELGGLKISTLRKLVDFLYTSEMEVSQEEAQDVLSAARQLRVSELESLQLEGGKLVKAPQGRRLNRECLQPTSAAPISARVVTPSHHPHTPLPTNQTPCPLGAIRLKSLGKEEGPQENNRQNADNLSGTLLLKRKARACPTPQEKNSSPSSHSQEPRENKNDTALDPTVLSPPSLYPSVDKHLLPRKIRLSRSKPSPGICTSKPSSILSGSSSVPATPGRRLWRQRSVNKETPEDKPKPGRASPLQSTPNPSGLGKTGGSRKRSPEVRAPNSDSAEEGQVGRVKLRKIVNGTCWEVVQETPLKNTQDSPQIPDPGGDFQEPSGTQPFSSNEQEMSPTRTELCQDSPMCTKLQDILVSASHSPDHPVVKSEFESSPELVEKEPMLAIDCREPYAFDTALLEQPCEAEEYRITSAAATSELEEILDFMLCGSDIEPPIGSLESPGAEGCRTPTYHLTETGKNWIEGEEWCLPDMELWPRELTELEKEPAGENRGPTELLSPLVMPSEVSEVLSVGGRWTPDLEITSSQPLDGQEDKLLHVSSLDTPQRSYGDLSPPCSNWVETGLEVSLTTDELLYPSPKAGKEVSGHSELLGSLPASSEEEEIDVVDWTAEGRLVPTTVPSVWPDPSSESETEVDILT

Domain & Motif Annotations

Compositional Bias

218..228; Polar residues; 229..238; Basic and acidic residues; 277..288; Low complexity; 303..313; Basic and acidic residues; 396..410; Polar residues; 702..712; Acidic residues

Domain (FT)

34..102; BTB

Region

157..176; Disordered; 212..355; Disordered; 374..410; Disordered; 653..676; Disordered; 691..712; Disordered

Clinical Relevance1

Antibody

HPA049325

Supporting Publications1

PMID	Title	Abstract
40748658	Exosomes released from senescent cells and circulatory exosomes isolated from human plasma reveal aging-associated proteomic and lipid signatures.	No abstract available