Protein detail
T4S5
Transmembrane 4 L6 family member 5 (Tetraspan transmembrane protein L6H)
Entry name T4S5 | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 1 | Transmembrane count 4 | Protein classification |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Transmembrane 4 L6 family member 5 (Tetraspan transmembrane protein L6H)
Protein Function
Transporters:Accessory Factors Involved in Transport
Transmembrane
10..30; Helical; 47..67; Helical; 91..111; Helical; 158..178; Helical
Transmembrane Count
4
Ensembl
Entrez Gene Symbol
Supporting publications (n)
1
EVMP confidence score
0.28
Fluorescence & Localization
Tissue SpecificesophagusCell SpecificEsophageal apical cellsSingle-Nuclei Brain Specificdeep-layer intratelencephalicSecretome LocationSecreted in other tissuesSecretome FunctionEnzyme
Function & Pathway
Protein Function
Transporters:Accessory Factors Involved in Transport
Cellular Component (3)
Molecular Function (2)
Biological Process (3)
Mediation Categories
Fusion and delivery mediation
Relations & Evidence22
Ligand-Receptor Signaling (21)
21 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | HPMR | Yes | Yes | |||
| tetraspanins | receptor | HPMR | Yes | Yes | |||
| tm4sf5 | receptor | HPMR | Yes | Yes | |||
| receptor | receptor | OmniPath | Yes | Yes | |||
| extracellular | extracellular | HPMR | Yes | ||||
| extracellular | extracellular | OmniPath | Yes | ||||
| intracellular | intracellular | GO_Intercell | Yes | ||||
| intracellular | intracellular | UniProt_location | Yes | ||||
| intracellular | intracellular | OmniPath | Yes | ||||
| transmembrane | transmembrane | UniProt_location | Yes |
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Sequence, Structure & Domains
Sequences
Length
197
Mass
20,823
Sequence
MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMVLCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCGIQLVNATIGVFCGDCRKKQDTPH
Domain & Motif Annotations
Region
91..197; Interaction with MTOR and CASTOR1
Protein Families
L6 tetraspanin family
Sequence Similarities
Belongs to the L6 tetraspanin family.
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 39408670 | Proteomic Characterization of Corneal Epithelial and Stromal Cell-Derived Extracellular Vesicles. | No related sentences available |