Protein detail
ZN185
Zinc finger protein 185 (LIM domain protein ZNF185) (P1-A)
Protein symbol ZN185 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification Plasma proteinsPredicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Zinc finger protein 185 (LIM domain protein ZNF185) (P1-A)
Protein Class
Plasma proteinsPredicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
SCELL
Gene Description
Zinc finger protein 185 with LIM domain
Chromosome
X
Position
152898067-152973481
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificbrainCell SpecificBrain inhibitory neuronsBlood Cell Specificmemory B-cellBlood Lineage SpecificB-cells
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Adhesion and uptake mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Mass spectrometry | 1 | 30915084 |
Sequence, Structure & Domains
Sequences
Length
689
Mass
73,525
Sequence
MSISALGGRTKGKPLPPGEEERNNVLKQMKVRTTLKGDKSWITKQDESEGRTIELPSGRSRATSFSSAGEVPKPRPPSTRAPTGYIIRGVFTKPIDSSSQPQQQFPKANGTPKSAASLVRTANAGPPRPSSSGYKMTTEDYKKLAPYNIRRSSTSGDTEEEEEEEVVPFSSDEQKRRSEAASGVLRRTAPREHSYVLSAAKKSTGPTQETQAPFIAKRVEVVEEDGPSEKSQDPPALARSTPGSNSADGGRTKASRAIWIECLPSMPSPAGSQELSSRGEEIVRLQILTPRAGLRLVAPDVEGMRSSPGNKDKEAPCSRELQRDLAGEEAFRAPNTDAARSSAQLSDGNVGSGATGSRPEGLAAVDIGSERGSSSATSVSAVPADRKSNSTAAQEDAKADPKGALADYEGKDVATRVGEAWQERPGAPRGGQGDPAVPAQQPADPSTPERQSSPSGSEQLVRRESCGSSVLTDFEGKDVATKVGEAWQDRPGAPRGGQGDPAVPTQQPADPSTPEQQNSPSGSEQFVRRESCTSRVRSPSSCMVTVTVTATSEQPHIYIPAPASELDSSSTTKGILFVKEYVNASEVSSGKPVSARYSNVSSIEDSFAMEKKPPCGSTPYSERTTGGICTYCNREIRDCPKITLEHLGICCHEYCFKCGICSKPMGDLLDQIFIHRDTIHCGKCYEKLF
Alternative Products
Event=Alternative splicing; Named isoforms=9; Name=1; IsoId=O15231-1; Sequence=Displayed; Name=2; IsoId=O15231-2; Sequence=VSP_039898, VSP_039899, VSP_039900, VSP_039901, VSP_039902; Name=3; IsoId=O15231-3; Sequence=VSP_039900; Name=4; IsoId=O15231-4; Sequence=VSP_043405; Name=5; IsoId=O15231-5; Sequence=VSP_045080, VSP_045081, VSP_043405; Name=6; IsoId=O15231-6; Sequence=VSP_047206; Name=7; IsoId=O15231-7; Sequence=VSP_047205; Name=8; IsoId=O15231-8; Sequence=VSP_047205, VSP_047206; Name=9; IsoId=O15231-9; Sequence=VSP_054773
Alternative Sequence
1..403; MSISALGGRTKGKPLPPGEEERNNVLKQMKVRTTLKGDKSWITKQDESEGRTIELPSGRSRATSFSSAGEVPKPRPPSTRAPTGYIIRGVFTKPIDSSSQPQQQFPKANGTPKSAASLVRTANAGPPRPSSSGYKMTTEDYKKLAPYNIRRSSTSGDTEEEEEEEVVPFSSDEQKRRSEAASGVLRRTAPREHSYVLSAAKKSTGPTQETQAPFIAKRVEVVEEDGPSEKSQDPPALARSTPGSNSADGGRTKASRAIWIECLPSMPSPAGSQELSSRGEEIVRLQILTPRAGLRLVAPDVEGMRSSPGNKDKEAPCSRELQRDLAGEEAFRAPNTDAARSSAQLSDGNVGSGATGSRPEGLAAVDIGSERGSSSATSVSAVPADRKSNSTAAQEDAKADPKG -> MAARDELGLGGDSLEAMPVPAARGRPRITNGPEELAAPSPA (in isoform 9); 1..140; Missing (in isoform 2); 1..135; Missing (in isoform 5); 141..144; YKKL -> MQRQ (in isoform 2); 177..205; RSEAASGVLRRTAPREHSYVLSAAKKSTG -> SS (in isoform 5); 205; G -> GS (in isoform 2 and isoform 3); 246..304; Missing (in isoform 4 and isoform 5); 246..275; Missing (in isoform 2); 276..304; Missing (in isoform 7 and isoform 8); 305..372; Missing (in isoform 2); 372; G -> GRLCAAASFASFLEDQDGHSANSQSCKPRPAAI (in isoform 6 and isoform 8)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
35..52; Basic and acidic residues; 95..114; Polar residues; 157..166; Acidic residues; 217..232; Basic and acidic residues; 310..331; Basic and acidic residues; 338..349; Polar residues; 373..382; Low complexity; 434..444; Low complexity; 448..458; Polar residues; 504..524; Polar residues
Domain (FT)
627..689; LIM zinc-binding
Region
1..253; Disordered; 298..534; Disordered