Protein detail
GPR39
G-protein coupled receptor 39
Entry name GPR39 | UniProt ID | EVMP confidence score 0.53 |
Supporting publications (n) 1 | Transmembrane count 7 | Protein classification G-protein coupled receptorsPredicted membrane proteinsTransporters |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
G-protein coupled receptor 39
Protein Class (3)
G-protein coupled receptorsPredicted membrane proteinsTransporters
Protein Function (2)
- Transporters
- G-protein coupled receptors:GPCRs excl olfactory receptors
Transmembrane
35..55; Helical; Name=1; 70..89; Helical; Name=2; 110..131; Helical; Name=3; 152..172; Helical; Name=4; 218..242; Helical; Name=5; 284..305; Helical; Name=6; 324..344; Helical; Name=7
Transmembrane Count
7
Ensembl
Entrez Gene Symbol
Gene Description
G protein-coupled receptor 39
Chromosome
2
Position
132416805-132646582
Supporting publications (n)
1
EVMP confidence score
0.53
Fluorescence & Localization
Tissue Specificchoroid plexusCell SpecificCytotrophoblastsSingle-Nuclei Brain SpecificastrocyteBlood Cell SpecificbasophilBlood Lineage Specificgranulocytes
Function & Pathway
Protein Function (2)
- Transporters
- G-protein coupled receptors:GPCRs excl olfactory receptors
Cellular Component
Molecular Function (3)
Biological Process (3)
Reactome (5)
Mediation Categories (2)
Clinical-translation mediationReceptor-signaling mediation
Relations & Evidence49
Ligand-Receptor Signaling (48)
48 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | connectomeDB2020 | Yes | Yes | |||
| receptor | receptor | iTALK | Yes | Yes | |||
| receptor | receptor | Almen2009 | Yes | Yes | |||
| receptor | receptor | CellCellInteractions | Yes | Yes | |||
| gpcr | receptor | GPCRdb | Yes | Yes | |||
| gpcr_orphan | receptor | HGNC | Yes | Yes | |||
| receptor | receptor | HGNC | Yes | Yes | |||
| transmembrane | transmembrane_predicted | Phobius | Yes |
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Sequence, Structure & Domains
Sequences
Length
453
Mass
51,329
Sequence
MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQSKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
Domain & Motif Annotations
Compositional Bias
418..435; Low complexity
Region
255..274; Disordered; 415..453; Disordered
Protein Families
G-protein coupled receptor 1 family
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family.
Clinical Relevance
Related Diseases
Biomarker
Investigative
Drugs
Antibody
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 34889606 | Surface Nanosieving Polyether Sulfone Particles with Graphene Oxide Encapsulation for the Negative Isolation toward Extracellular Vesicles. | No related sentences available |