Protein detail
CTR4
Cationic amino acid transporter 4 (CAT-4) (CAT4) (Solute carrier family 7 member 4)
Entry name CTR4 | UniProt ID | EVMP confidence score 0.40 |
Supporting publications (n) 1 | Transmembrane count 13 | Protein classification Predicted membrane proteinsTransporters |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Cationic amino acid transporter 4 (CAT-4) (CAT4) (Solute carrier family 7 member 4)
Protein Class (2)
Predicted membrane proteinsTransporters
Protein Function
Transporters:Electrochemical Potential-driven transporters
Transmembrane
42..62; Helical; 66..86; Helical; 113..133; Helical; 197..217; Helical; 229..249; Helical; 270..290; Helical; 318..338; Helical; 365..385; Helical; 391..411; Helical; 478..498; Helical; 508..528; Helical; 539..559; Helical; 567..587; Helical
Transmembrane Count
13
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
CAT-4HCAT3VH
Gene Description
Solute carrier family 7 member 4
Chromosome
22
Position
21028718-21032840
Supporting publications (n)
1
EVMP confidence score
0.40
Fluorescence & Localization
Cell SpecificLate spermatids
Function & Pathway
Protein Function
Transporters:Electrochemical Potential-driven transporters
Cellular Component (2)
Molecular Function (2)
Biological Process (3)
Mediation Categories
Fusion and delivery mediation
Relations & Evidence18
Ligand-Receptor Signaling (17)
17 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | OmniPath | Yes | ||||
| transporter | transporter | Surfaceome | Yes | ||||
| solute_carrier | transporter | Almen2009 | Yes | ||||
| slc7 | transporter | Surfaceome | Yes | ||||
| apc | transporter | Surfaceome | Yes | ||||
| slc | transporter | Surfaceome | Yes | ||||
| transporter | transporter | OmniPath | Yes | ||||
| transmembrane | transmembrane | UniProt_location | |||||
| transmembrane | transmembrane | UniProt_topology | |||||
| transmembrane | transmembrane | UniProt_keyword |
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Sequence, Structure & Domains
Sequences
Length
635
Mass
68,268
Sequence
MARGLPTIASLARLCQKLNRLKPLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAVLLSFGVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNVLLEYIIGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLASAFVSCGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGVMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGPASPGPLTKQQSSFSDHLQLVGTVHASVPEPGELKPALRPYLGFLDGYSPGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQYREDLFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHSKENQRELPGLNSTHYVVFPRGSLEETVQAMQPPSQAPAQDPGHME
Domain & Motif Annotations
Protein Families (2)
- Amino acid-polyamine-organocation (APC) superfamily
- Cationic amino acid transporter (CAT) (TC 2.A.3.3) family
Sequence Similarities
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
Clinical Relevance
Antibody
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 36763158 | Pilot study investigating BP-180 in extracellular vesicles derived from blister fluid of bullous pemphigoid patients. | No related sentences available |