Protein detail
GAS7
Growth arrest-specific protein 7 (GAS-7)
Protein symbol GAS7 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification Cancer-related genesDisease related genesPredicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Growth arrest-specific protein 7 (GAS-7)
Protein Class
Cancer-related genesDisease related genesPredicted intracellular proteins
Protein Function
- Disease related genes
- Predicted intracellular proteins
- Cancer-related genes
Ensembl
Entrez Gene Symbol
Gene Synonym
KIAA0394MGC1348
Gene Description
Growth arrest specific 7
Chromosome
17
Position
9910606-10198606
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificbrainCell SpecificBrain excitatory neurons
Function & Pathway
Protein Function
- Disease related genes
- Predicted intracellular proteins
- Cancer-related genes
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Fusion and delivery mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
7 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | LOCATE | No | No | No | No | No |
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| fbar_actin_dynamics_endocytosis | intracellular_intercellular_related | HGNC | Yes | No | No | No | No |
| intracellular_intercellular_related | intracellular_intercellular_related | OmniPath | Yes | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Polymer Precipitation | Western blotting | 1 | 38731868 |
Sequence, Structure & Domains
Sequences
Length
476
Mass
54,371
Sequence
MSGARCRTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLLEKPGMVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGSHRSSLPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI
Alternative Products
Event=Alternative splicing; Named isoforms=4; Name=3; IsoId=O60861-3; Sequence=Displayed; Name=1; IsoId=O60861-1; Sequence=VSP_035988; Name=2; Synonyms=GAS7-CB; IsoId=O60861-2; Sequence=VSP_006802, VSP_006803; Name=4; IsoId=O60861-4; Sequence=VSP_044294, VSP_044295
Alternative Sequence
1..140; Missing (in isoform 2); 1..64; Missing (in isoform 1); 1..60; Missing (in isoform 4); 61; E -> M (in isoform 4); 141..156; PPETAHMSVRKSTGDS -> MSNMENSFDDVSCLSP (in isoform 2)
3D Structural Models
Helix
54..56
Beta Strand
5..9; 28..32; 40..43; 49..52; 57..59; 84..87; 93..96; 98..100; 103..107
3D Structure
NMR spectroscopy (2)
Domain & Motif Annotations
Compositional Bias
108..120; Low complexity; 150..171; Polar residues
Coiled Coil
309..419
Domain (FT)
1..62; SH3; 77..110; WW; 196..456; F-BAR
Region
100..171; Disordered