Protein detail
MFA3L
Microfibrillar-associated protein 3-like (Testis development protein NYD-SP9)
Protein symbol MFA3L | UniProt ID | EVMP score 0.25 |
Frequency 1 | Transmembrane count 1 | Protein classification Predicted intracellular proteinsPredicted membrane proteins |
Basic Information
Protein Names
Microfibrillar-associated protein 3-like (Testis development protein NYD-SP9)
Protein Class
Predicted intracellular proteinsPredicted membrane proteins
Protein Function
Predicted intracellular proteins
Transmembrane
150..172; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
KIAA0626NYD-sp9
Gene Description
Microfibril associated protein 3 like
Chromosome
4
Position
169986597-170033031
Frequency
1
EVMP Score
0.25
Fluorescence & Localization
Cell SpecificEsophageal apical cells
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Canonical Pathways
M16801 Sig regulation of the actin cytoskeleton by rho gtpases
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
1 record.
| Substrate Gene Symbol | Enzyme Gene Symbol | Enzyme UniProt ID | Residue Type | Residue Offset | Modification | Database | References |
|---|---|---|---|---|---|---|---|
| MFAP3L | EGFR | P00533 | Y | 287 | phosphorylation | Sparser_ProtMapperProtMapper | ProtMapper:24735981 |
Ligand-Receptor Signaling
26 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| cell_surface | cell_surface | OmniPath | No | No | No | Yes | No |
| receptor | receptor | Cellinker | No | Yes | No | Yes | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | Yes | No |
| transmembrane_phobius | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
| transmembrane_sosui | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
| transmembrane_tmhmm | transmembrane_predicted | Almen2009 | No | No | No | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
409
Mass
45,380
Sequence
MDRLKSHLTVCFLPSVPFLILVSTLATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMGVYYMVVCLVAFTIVMVLNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEAADRDEVYTIPNSLKRSDSPAADSDASSLHEQPQQIAIKVSVHPQSKKEHADDQEGGQFEVKDVEETELSAEHSPETAEPSTDVTSTELTSEEPTPVEVPDKVLPPAYLEATEPAVTHDKNTCIIYESHV
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O75121-1; Sequence=Displayed; Name=2; IsoId=O75121-2; Sequence=VSP_011100; Name=3; IsoId=O75121-3; Sequence=VSP_014094, VSP_014095
Alternative Sequence
1..103; Missing (in isoform 2); 101..102; KW -> RL (in isoform 3); 103..409; Missing (in isoform 3)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
339..355; Basic and acidic residues; 363..377; Low complexity
Domain (FT)
47..141; Ig-like C2-type
Region
292..311; Disordered; 320..385; Disordered