Protein detail
HSBP1
Heat shock factor-binding protein 1 (Nasopharyngeal carcinoma-associated antigen 13) (NPC-A-13)
Protein symbol HSBP1 | UniProt ID | EVMP score 0.50 |
Frequency 6 | Transmembrane count | Protein classification |
Basic Information
Protein Names
Heat shock factor-binding protein 1 (Nasopharyngeal carcinoma-associated antigen 13) (NPC-A-13)
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Frequency
6
EVMP Score
0.50
Fluorescence & Localization
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
5 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | LOCATE | No | No | No | No | No |
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
2 records.
| Source Protein Symbol | Source UniProt ID | Target Protein Symbol | Target UniProt ID | Is Directed | Is Stimulation | Is Inhibition | Database | References |
|---|---|---|---|---|---|---|---|---|
| HSBP1 | O75506 | HSF1 | Q00613 | Yes | No | Yes | SIGNORHPRDSPIKE_LCLit-BM-17SPIKE | SPIKE_LC:9869631Lit-BM-17:9649501SPIKE:9649501SPIKE_LC:9649501SPIKE:9869631HPRD:9649501SIGNOR:9649501SPIKE_LC:16189514 |
| HSBP1 | O75506 | COMPLEX:A8K0Z3_Q12768_Q2M389_Q9Y3C0_Q9Y4E1 | Yes | Yes | No | SIGNOR | SIGNOR:29844016 |
Protein Complex Composition
4 records.
| Component Name | Component Gene Symbols | Component UniProt ID | Stoichiometry | Database | Database IDs | References |
|---|---|---|---|---|---|---|
| ATP5F1AATP5F1BATP5F1CATP5F1EATP5MEATP5MFATP5MGATP5PBATP5PDATP5POHSBP1TSPAN6 | O43657O75506O75947O75964P06576P24539P25705P36542P48047P56134P56381P56385 | 1:1:1:1:1:1:1:1:1:1:1:1 | NetworkBlastCompleat | Compleat:HC7327 | ||
| HSBP1 | O75506 | 2 | PDB | PDB:3ci9 | ||
| HSBP1RAB2ARAB4ARAB5ARAB7ARBSNVPS45 | O75506P20338P20339P51149P61019Q9H1K0Q9NRW7 | 1:1:1:1:1:1:1 | NetworkBlastCompleat | Compleat:HC5056 | ||
| HSBP1RAB14RAB4ARAB5ARAB7ARBSNVPS45 | O75506P20338P20339P51149P61106Q9H1K0Q9NRW7 | 1:1:1:1:1:1:1 | NetworkBlastCompleat | Compleat:HC7491 |
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometrySmall R sequencing (Illumi HiSeq 2000 (Solexa) | 1 | 40326690 |
Sequence, Structure & Domains
Sequences
Length
76
Mass
8,544
Sequence
MAETDPKTVQDLTSVVQTLLQQMQDKFQTMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELESENKIPATQKS
3D Structural Models
Helix
9..46
3D Structure
X-ray crystallography (1)
Domain & Motif Annotations
Protein Families
HSBP1 family
Sequence Similarities
Belongs to the HSBP1 family.
Clinical Relevance
Interaction Protein
ENSG00000120860ENSG00000123395ENSG00000204536ENSG00000254999
Interaction Count
4
Interaction Dataset
intact_biogrid_bioplexbiogrid_opencellintact_biogrid