Protein detail
ZMY10
Zinc finger MYND domain-containing protein 10 (Protein BLu)
Entry name ZMY10 | UniProt ID | EVMP confidence score 0.50 |
Supporting publications (n) 2 | Transmembrane count | Protein classification |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information6
Protein Names
Zinc finger MYND domain-containing protein 10 (Protein BLu)
Protein Function (3)
- Disease related genes
- Human disease related genes:Respiratory diseases:Tracheobronchial diseases
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Supporting publications (n)
2
EVMP confidence score
0.50
Fluorescence & Localization2
Tissue SpecifictestisCell SpecificDifferentiating spermatogonia
Function & Pathway6
Protein Function (3)
- Disease related genes
- Human disease related genes:Respiratory diseases:Tracheobronchial diseases
- Predicted intracellular proteins
Cellular Component (4)
Molecular Function (4)
Biological Process (3)
Canonical Pathways (3)
- M82 Pid ret pathway
- M276 Pid fgf pathway
- M100 Pid shp2 pathway
Mediation Categories
Fusion and delivery mediation
Relations & Evidence8
Ligand-Receptor Signaling (7)
7 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| apical_cell_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | No | No |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity Capture | Mass spectrometry | 17 | 4018949738113368373224754106825333592500328543153801459538891077325607234130796836146834322309703087572238207106345762463720451539001700 |
Sequence, Structure & Domains13
Sequences
Length
440
Mass
50,344
Sequence
MGDLELLLPGEAEVLVRGLRSFPLREMGSEGWNQQHENLEKLNMQAILDATVSQGEPIQELLVTHGKVPTLVEELIAVEMWKQKVFPVFCRVEDFKPQNTFPIYMVVHHEASIINLLETVFFHKEVCESAEDTVLDLVDYCHRKLTLLVAQSGCGGPPEGEGSQDSNPMQELQKQAELMEFEIALKALSVLRYITDCVDSLSLSTLSRMLSTHNLPCLLVELLEHSPWSRREGGKLQQFEGSRWHTVAPSEQQKLSKLDGQVWIALYNLLLSPEAQARYCLTSFAKGRLLKLRAFLTDTLLDQLPNLAHLQSFLAHLTLTETQPPKKDLVLEQIPEIWERLERENRGKWQAIAKHQLQHVFSPSEQDLRLQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSRCQNEWYCCRECQVKHWEKHGKTCVLAAQGDRAK
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; Synonyms=Lung; IsoId=O75800-1; Sequence=Displayed; Name=2; Synonyms=Testis; IsoId=O75800-2; Sequence=VSP_003328
Alternative Sequence
200..234; SLSLSTLSRMLSTHNLPCLLVELLEHSPWSRREGG -> RQWSVSQPPQLAHLKRIQRLHPVCWFLSPG (in isoform 2)
3D Structural Models
Turn
406..408
Helix
416..421; 423..429
Beta Strand
395..397; 411..415
3D Structure
NMR spectroscopy (2)
Domain & Motif Annotations
Zinc Finger
394..430; MYND-type
Region
366..440; Interaction with DNAAF11
Protein Families
ZMYND10 family
Sequence Similarities
Belongs to the ZMYND10 family.
Clinical Relevance3
Interaction Protein
ENSG00000166925
Interaction Count
1
Interaction Dataset
intact_biogrid
Supporting Publications2
| PMID | Title | Abstract |
|---|---|---|
| 37922300 | Proteomic profiling of urinary extracellular vesicles differentiates breast cancer patients from healthy women. | No abstract available |
| 40098346 | Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays. | No abstract available |