Protein detail
SCEL
Sciellin
Protein symbol SCEL | UniProt ID | EVMP score 0.72 |
Frequency 20 | Transmembrane count | Protein classification Plasma proteinsPredicted intracellular proteins |
Basic Information
Protein Names
Sciellin
Protein Class
Plasma proteinsPredicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
FLJ21667MGC22531
Gene Description
Sciellin
Chromosome
13
Position
77535674-77645263
Frequency
20
EVMP Score
0.72
Fluorescence & Localization
Tissue SpecificbrainCell SpecificCytotrophoblasts
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Receptor-signaling mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
8 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | Yes | No | No |
| intracellular | intracellular | GO_Intercell | No | No | Yes | No | No |
| intracellular | intracellular | UniProt_location | No | No | Yes | No | No |
| intracellular | intracellular | OmniPath | No | No | Yes | No | No |
| secreted | secreted | Cellinker | No | No | Yes | No | No |
| secreted | secreted | OmniPath | No | No | Yes | No | No |
| ligand | ligand | Cellinker | Yes | No | Yes | No | No |
| ligand | ligand | OmniPath | Yes | No | Yes | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 1 | 32002171 |
Sequence, Structure & Domains
Sequences
Length
688
Mass
77,552
Sequence
MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNRSMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTRRREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSKIMAKWIP
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=O95171-1; Sequence=Displayed; Name=2; IsoId=O95171-2; Sequence=VSP_035980; Name=3; IsoId=O95171-3; Sequence=VSP_045288, VSP_045289
Alternative Sequence
160..181; Missing (in isoform 3); 231..251; RSQDLDNIVKVATSLQRSDKG -> S (in isoform 2); 367..386; Missing (in isoform 3)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
1..25; Polar residues; 140..154; Low complexity; 186..195; Pro residues; 358..373; Basic and acidic residues
Repeat
251..266; 1; 267..286; 2; 287..306; 3; 307..326; 4; 327..346; 5; 347..366; 6; 367..386; 7; 387..406; 8; 407..426; 9; 427..446; 10; 447..465; 11; 466..484; 12; 485..504; 13; 505..523; 14; 524..543; 15; 544..563; 16
Domain (FT)
619..685; LIM zinc-binding
Region
1..29; Disordered; 134..231; Disordered; 251..563; 16 X approximate tandem repeats; 340..373; Disordered