Protein detail
VNN2
Pantetheine hydrolase VNN2 (EC 3.5.1.92) (Glycosylphosphatidyl inositol-anchored protein GPI-80) (Protein FOAP-4) (Vascular non-inflammatory molecule 2) (Vanin-2)
Protein symbol VNN2 | UniProt ID | EVMP score 0.25 |
Frequency 1 | Transmembrane count | Protein classification |
Basic Information
Protein Names
Pantetheine hydrolase VNN2 (EC 3.5.1.92) (Glycosylphosphatidyl inositol-anchored protein GPI-80) (Protein FOAP-4) (Vascular non-inflammatory molecule 2) (Vanin-2)
Protein Function
- Enzymes
- Predicted intracellular proteins
- ENZYME proteins:Hydrolases
Ensembl
Entrez Gene Symbol
Frequency
1
EVMP Score
0.25
Fluorescence & Localization
Tissue SpecificbrainCell SpecificLate spermatids
Function & Pathway
Protein Function
- Enzymes
- Predicted intracellular proteins
- ENZYME proteins:Hydrolases
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Immune mediationMetabolism mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
21 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | Yes | Yes |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | Yes | Yes |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | CSPA | No | No | No | Yes | Yes |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | OmniPath | No | No | No | Yes | Yes |
| plasma_membrane_peripheral | plasma_membrane_peripheral | CSPA | No | No | No | Yes | Yes |
| plasma_membrane_peripheral | plasma_membrane_peripheral | OmniPath | No | No | No | Yes | Yes |
| cell_surface | cell_surface | Surfaceome | No | No | No | Yes | Yes |
| cell_surface | cell_surface | OmniPath | No | No | No | Yes | Yes |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | Yes | Yes |
| transmembrane_phobius | transmembrane_predicted | Almen2009 | No | No | No | Yes | Yes |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Sequence, Structure & Domains
Sequences
Length
520
Mass
58,503
Sequence
MVTSSFPISVAVFALITLQVGTQDSFIAAVYEHAVILPNKTETPVSQEDALNLMNENIDILETAIKQAAEQGARIIVTPEDALYGWKFTRETVFPYLEDIPDPQVNWIPCQDPHRFGHTPVQARLSCLAKDNSIYVLANLGDKKPCNSRDSTCPPNGYFQYNTNVVYNTEGKLVARYHKYHLYSEPQFNVPEKPELVTFNTAFGRFGIFTCFDIFFYDPGVTLVKDFHVDTILFPTAWMNVLPLLTAIEFHSAWAMGMGVNLLVANTHHVSLNMTGSGIYAPNGPKVYHYDMKTELGKLLLSEVDSHPLSSLAYPTAVNWNAYATTIKPFPVQKNTFRGFISRDGFNFTELFENAGNLTVCQKELCCHLSYRMLQKEENEVYVLGAFTGLHGRRRREYWQVCTLLKCKTTNLTTCGRPVETASTRFEMFSLSGTFGTEYVFPEVLLTEIHLSPGKFEVLKDGRLVNKNGSSGPILTVSLFGRWYTKDSLYSSCGTSNSAITYLLIFILLMIIALQNIVML
Alternative Products
Event=Alternative splicing; Named isoforms=6; Name=1; IsoId=O95498-1; Sequence=Displayed; Name=2; Synonyms=GPI-80 variant protein 3; IsoId=O95498-2; Sequence=VSP_038557; Name=3; Synonyms=GPI-80 variant protein 2; IsoId=O95498-3; Sequence=VSP_038558, VSP_038559; Name=4; Synonyms=GPI-80 variant protein 1; IsoId=O95498-4; Sequence=VSP_038556, VSP_038560; Name=5; Synonyms=GPI-80 variant protein 4; IsoId=O95498-5; Sequence=VSP_038554, VSP_038555; Name=6; IsoId=O95498-6; Sequence=VSP_044912
Alternative Sequence
1..53; Missing (in isoform 6); 116..119; FGHT -> SAQC (in isoform 5); 120..520; Missing (in isoform 5); 180..400; Missing (in isoform 2); 180..195; YHLYSEPQFNVPEKPE -> EVVFMHQMVPKCIIMT (in isoform 4); 180..192; YHLYSEPQFNVPE -> ETLQSVKRSFAVI (in isoform 3); 193..520; Missing (in isoform 3); 196..520; Missing (in isoform 4)
3D Structural Models
Domain & Motif Annotations
Domain (FT)
31..306; CN hydrolase
Protein Families
- Carbon-nitrogen hydrolase superfamily
- BTD/VNN family
Sequence Similarities
Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.