Protein detail
TSN15
Tetraspanin-15 (Tspan-15) (Tetraspan NET-7) (Transmembrane 4 superfamily member 15)
Protein symbol TSN15 | UniProt ID | EVMP score 0.88 |
Frequency 32 | Transmembrane count 4 | Protein classification Predicted membrane proteinsTransporters |
Basic Information
Protein Names
Tetraspanin-15 (Tspan-15) (Tetraspan NET-7) (Transmembrane 4 superfamily member 15)
Protein Class
Predicted membrane proteinsTransporters
Protein Function
Transporters:Accessory Factors Involved in Transport
Transmembrane
24..44; Helical; 63..83; Helical; 94..114; Helical; 236..256; Helical
Transmembrane Count
4
Ensembl
Entrez Gene Symbol
Gene Synonym
NET-7TM4SF15
Gene Description
Tetraspanin 15
Chromosome
10
Position
69451465-69507666
Frequency
32
EVMP Score
0.88
Fluorescence & Localization
Cell SpecificLate primary spermatocytesBlood Cell SpecificbasophilBlood Lineage Specificgranulocytes
Function & Pathway
Protein Function
Transporters:Accessory Factors Involved in Transport
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Fusion and delivery mediationMetabolism mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
30 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | Cellinker | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | HPMR | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | OmniPath | No | No | No | Yes | No |
| cell_surface | cell_surface | Surfaceome | No | No | No | Yes | No |
| cell_surface | cell_surface | OmniPath | No | No | No | Yes | No |
| receptor | receptor | CellCellInteractions | No | Yes | No | Yes | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Western blottingMORPH | 1 | 32089743 |
Sequence, Structure & Domains
Sequences
Length
294
Mass
33,165
Sequence
MPRGDSEQVRYCARFSYLWLKFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAFLAPAIILILLGVVMFMVSFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYYDDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTMCGYKTIDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLLTLLYITRVEDIIMEHSVTDGLLGPGAKPSVEAAGTGCCLCYPN
3D Structural Models
Turn
85..87; 134..137; 167..169; 196..199; 211..213
Helix
14..50; 62..84; 89..115; 117..133; 139..151; 160..165; 183..185; 207..210; 219..229; 231..266
Beta Strand
156..159; 174..177; 190..192; 203..205
3D Structure
Electron microscopy (1); X-ray crystallography (2)
Domain & Motif Annotations
Protein Families
Tetraspanin (TM4SF) family
Sequence Similarities
Belongs to the tetraspanin (TM4SF) family.