Protein detail
BY55
CD160 antigen (Natural killer cell receptor BY55) (CD antigen CD160) [Cleaved into: CD160 antigen, soluble form]
Entry name BY55 | UniProt ID | EVMP confidence score 0.25 |
Supporting publications (n) 3 | Transmembrane count | Protein classification |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information6
Protein Names
CD160 antigen (Natural killer cell receptor BY55) (CD antigen CD160) [Cleaved into: CD160 antigen, soluble form]
Protein Function (2)
- Predicted secreted proteins
- CD markers
Ensembl
Entrez Gene Symbol
Supporting publications (n)
3
EVMP confidence score
0.25
Fluorescence & Localization3
Tissue SpecifickidneyCell SpecificDistal convoluted tubule cellsSingle-Nuclei Brain Specificpericyte
Function & Pathway6
Protein Function (2)
- Predicted secreted proteins
- CD markers
Cellular Component (3)
Molecular Function (7)
Biological Process (3)
Reactome (2)
Mediation Categories (4)
Adhesion and uptake mediationFusion and delivery mediationImmune mediationReceptor-signaling mediation
Relations & Evidence40
Ligand-Receptor Signaling (38)
38 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | CellPhoneDB | No | Yes | Yes | No | Yes |
| receptor | receptor | ICELLNET | No | Yes | Yes | No | Yes |
| hla_recognition | receptor | ICELLNET | No | Yes | Yes | No | Yes |
| receptor | receptor | OmniPath | No | Yes | Yes | No | Yes |
| extracellular | extracellular | OmniPath | No | No | Yes | No | Yes |
| intracellular | intracellular | LOCATE | No | No | Yes | No | Yes |
| intracellular | intracellular | GO_Intercell | No | No | Yes | No | Yes |
| intracellular | intracellular | OmniPath | No | No | Yes | No | Yes |
| cell_surface_ligand | cell_surface_ligand | CellChatDB | Yes | No | Yes | No | Yes |
| cell_surface_ligand | cell_surface_ligand | OmniPath | Yes | No | Yes | No | Yes |
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Protein Complex Composition (1)
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Mass spectrometry | 0 |
Sequence, Structure & Domains10
Sequences
Length
181
Mass
19,810
Sequence
MLLEPGRGCCALAILLAIVDIQSGGCINITSSASQEGTRLNLICTVWHKKEEAEGFVVFLCKDRSGDCSPETSLKQLRLKRDPGIDGVGEISSQLMFTISQVTPLHSGTYQCCARSQKSGIRLQGHFFSILFTETGNYTVTGLKQRQHLEFSHNEGTLSSGFLQEKVWVMLVTSLVALQAL
Alternative Products
Event=Alternative splicing; Named isoforms=4; Name=1; Synonyms=CD160; IsoId=O95971-1; Sequence=Displayed; Name=2; Synonyms=CD160deltaIg; IsoId=O95971-2; Sequence=VSP_060018; Name=3; Synonyms=CD160-TM; IsoId=O95971-3; Sequence=VSP_060019; Name=4; Synonyms=CD160deltaIg-TM; IsoId=O95971-4; Sequence=VSP_060017
Alternative Sequence
25..181; GCINITSSASQEGTRLNLICTVWHKKEEAEGFVVFLCKDRSGDCSPETSLKQLRLKRDPGIDGVGEISSQLMFTISQVTPLHSGTYQCCARSQKSGIRLQGHFFSILFTETGNYTVTGLKQRQHLEFSHNEGTLSSGFLQEKVWVMLVTSLVALQAL -> ETGNYTVTGLKQRQHLEFSHNEGTLSSGFLQEKVWVMLVTSLVALQGMSKRAVSTPSNEGAIIFLPPWLFSRRRRLERMSRGREKCYSSPGYPQESSNQFH (in isoform 4); 25..133; Missing (in isoform 2); 180..181; AL -> GMSKRAVSTPSNEGAIIFLPPWLFSRRRRLERMSRGREKCYSSPGYPQESSNQFH (in isoform 3)
3D Structural Models
Turn
117..119
Helix
50..52; 70..72; 104..106
Beta Strand
28..36; 39..47; 54..63; 74..77; 88..101; 108..116; 122..124; 128..132; 138..141
3D Structure
X-ray crystallography (4)
Domain & Motif Annotations
Domain (FT)
25..133; Ig-like V-type
Supporting Publications3
| PMID | Title | Abstract |
|---|---|---|
| 33936570 | Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer-based precipitation and size exclusion chromatography. | No abstract available |
| 37670049 | Proteomic and functional characterisation of extracellular vesicles from collagen VI deficient human fibroblasts reveals a role in cell motility. | No abstract available |
| 38014595 | Proteome and immune responses of extracellular vesicles derived from macrophages infected with the periodontal pathogen Tannerella forsythia. | No abstract available |