Protein detail
GLPA
Glycophorin-A (MN sialoglycoprotein) (PAS-2) (Sialoglycoprotein alpha) (CD antigen CD235a)
Protein symbol GLPA | UniProt ID | EVMP score 0.50 |
Frequency 1 | Transmembrane count 1 | Protein classification Blood group antigen proteinsCD markersPredicted membrane proteinsTransporters |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Glycophorin-A (MN sialoglycoprotein) (PAS-2) (Sialoglycoprotein alpha) (CD antigen CD235a)
Protein Class
Blood group antigen proteinsCD markersPredicted membrane proteinsTransporters
Protein Function
- Blood group antigen proteins
- CD markers
- Transporters:Accessory Factors Involved in Transport
Transmembrane
92..114; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
CD235aGPAMNMNS
Gene Description
Glycophorin A (MNS blood group)
Chromosome
4
Position
144109303-144140751
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Cell SpecificMyonucleiSingle-Nuclei Brain Specificcommitted oligodendrocyte precursor
Function & Pathway
Protein Function
- Blood group antigen proteins
- CD markers
- Transporters:Accessory Factors Involved in Transport
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Immune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
24 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane | transmembrane | LOCATE | No | No | No | Yes | No |
| transmembrane | transmembrane | Ramilowski_location | No | No | No | Yes | No |
| transmembrane | transmembrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | Membranome | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | OmniPath | No | No | No | Yes | No |
| cell_surface | cell_surface | Surfaceome | No | No | No | Yes | No |
| cell_surface | cell_surface | OmniPath | No | No | No | Yes | No |
| receptor | receptor | CellCellInteractions | No | Yes | No | Yes | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyImmunoaffinity Capture | Mass spectrometry | 24 | 364064913893867439290459265384823822545339436214327954143873186823585444254712073007131833709510407508963768636638490958400983464120109034186243307605383792230040311616400914553813660138564289 |
Sequence, Structure & Domains
Sequences
Length
150
Mass
16,430
Sequence
MYGKIIFVLLLSEIVSISALSTTEVAMHTSTSSSVTKSYISSQTNDTHKRDTYAATPRAHEVSEISVRTVYPPEEETGERVQLAHHFSEPEITLIIFGVMAGVIGTILLISYGIRRLIKKSPSDVKPLPSPDTDVPLSSVEIENPETSDQ
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=P02724-1; Sequence=Displayed; Name=2; IsoId=P02724-2; Sequence=VSP_047822; Name=3; IsoId=P02724-3; Sequence=VSP_047823
Alternative Sequence
1..26; Missing (in isoform 2); 13..45; Missing (in isoform 3)
3D Structural Models
Helix
92..115
Beta Strand
84..86
3D Structure
Electron microscopy (11); NMR spectroscopy (3); X-ray crystallography (2)
Domain & Motif Annotations
Region
121..150; Disordered
Protein Families
Glycophorin A family
Sequence Similarities
Belongs to the glycophorin A family.