Protein detail
ONCO
Oncomodulin-1 (OM) (Parvalbumin beta)
Entry name ONCO | UniProt ID | EVMP confidence score 0.40 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Oncomodulin-1 (OM) (Parvalbumin beta)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
OCM1
Gene Description
Oncomodulin
Chromosome
7
Position
5879827-5886363
Supporting publications (n)
1
EVMP confidence score
0.40
Fluorescence & Localization
Tissue SpecificintestineBrain Regional Specificchoroid plexusCell SpecificEnterocytes
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function (2)
Biological Process (3)
Canonical Pathways (3)
- M5880 Naba ecm affiliated
- M5885 Naba matrisome associated
- M5889 Naba matrisome
Mediation Categories
Other mediation
Relations & Evidence4
Ligand-Receptor Signaling (3)
3 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | OmniPath |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 1 | 40740986 |
Sequence, Structure & Domains
Sequences
Length
109
Mass
12,184
Sequence
MSITDVLSADDIAAALQECRDPDTFEPQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS
3D Structural Models
Turn
4..6; 36..38
Helix
8..18; 27..33; 41..51; 61..64; 68..70; 80..90; 100..108
Beta Strand
56..58; 92..96
3D Structure
NMR spectroscopy (1)
Domain & Motif Annotations
Domain (FT)
39..74; EF-hand 1; 78..109; EF-hand 2
Protein Families
Parvalbumin family
Sequence Similarities
Belongs to the parvalbumin family.
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 23161513 | Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. | Exosomes from mutant KRAS cells contain many tumor-promoting proteins, including KRAS, EGFR, SRC family kinases, and integrins. |