Protein detail

ZNF10

Zinc finger protein 10 (Zinc finger protein KOX1)

Entry name ZNF10	UniProt ID P21506	EVMP score 0.38
Frequency 2	Transmembrane count	Protein classification Predicted intracellular proteinsTranscription factors

EVMP score: annotation confidence score.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information

Protein Names

Zinc finger protein 10 (Zinc finger protein KOX1)

Protein Class

Predicted intracellular proteinsTranscription factors

Protein Function

Predicted intracellular proteins
Transcription factors:Zinc-coordinating DNA-binding domains

Ensembl

ENSG00000256223

Entrez Gene Symbol

ZNF10

Gene Synonym

KOX1

Gene Description

Zinc finger protein 10

Chromosome

Position

133130575-133159465

Frequency

EVMP Score

0.38

Fluorescence & Localization

Cell SpecificEpididymal basal cellsSingle-Nuclei Brain Specificendothelial cell

Function & Pathway

Protein Function

Predicted intracellular proteins
Transcription factors:Zinc-coordinating DNA-binding domains

Cellular Component

Molecular Function

Biological Process

Reactome

R-hsa-73857 rna polymerase ii transcription

Mediation Categories

Other mediation

Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	UniProt_location	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No

Regulatory Interaction Network

0 records.

Protein Complex Composition

8 records.

Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs
CEP85L DUSP11 KLHL40 KLHL41 ZNF106 ZNF81	O60662 O75319 P51508 Q2TBA0 Q5SZL2 Q9H2Y7	0:0:0:0:0:0	hu.MAP2
CEP85L KLHL40 KLHL41 ZNF106 ZNF81	O60662 P51508 Q2TBA0 Q5SZL2 Q9H2Y7	0:0:0:0:0	hu.MAP2
BRCA1 CREB1 PIAS1 RAD51 SAE1 SUMO2 SUMO3 TP53 UBA2 UBE2I ZNF106	O75925 P04637 P16220 P38398 P55854 P61956 P63279 Q06609 Q9H2Y7 Q9UBE0 Q9UBT2	1:1:1:1:1:1:1:1:1:1:1	NetworkBlastCompleat	Compleat:HC4911
HRC ZNF101	P23327 Q8IZC7	0:0	hu.MAP2
BMS1 BOP1 DDX10 DDX56 KNOP1 UTP18 UTP3 ZNF106	Q13206 Q14137 Q14692 Q1ED39 Q9H2Y7 Q9NQZ2 Q9NY93 Q9Y5J1	0:0:0:0:0:0:0:0	hu.MAP2
DDX10 KNOP1 ZNF106	Q13206 Q1ED39 Q9H2Y7	0:0:0	hu.MAP2
KNOP1 ZNF106	Q1ED39 Q9H2Y7	0:0	hu.MAP2
CCDC71L HES6 NEUROG2 NEUROG3 PKDCC ZNF100	Q504Y2 Q8IYN0 Q8N9Z2 Q96HZ4 Q9H2A3 Q9Y4Z2	0:0:0:0:0:0	hu.MAP2

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
	Mass spectrometry	0

Sequence, Structure & Domains

Sequences

Length

573

Mass

66,455

Sequence

MDAKSLTAWSRTLVTFKDVFVDFTREEWKLLDTAQQIVYRNVMLENYKNLVSLGYQLTKPDVILRLEKGEEPWLVEREIHQETHPDSETAFEIKSSVSSRSIFKDKQSCDIKMEGMARNDLWYLSLEEVWKCRDQLDKYQENPERHLRQVAFTQKKVLTQERVSESGKYGGNCLLPAQLVLREYFHKRDSHTKSLKHDLVLNGHQDSCASNSNECGQTFCQNIHLIQFARTHTGDKSYKCPDNDNSLTHGSSLGISKGIHREKPYECKECGKFFSWRSNLTRHQLIHTGEKPYECKECGKSFSRSSHLIGHQKTHTGEEPYECKECGKSFSWFSHLVTHQRTHTGDKLYTCNQCGKSFVHSSRLIRHQRTHTGEKPYECPECGKSFRQSTHLILHQRTHVRVRPYECNECGKSYSQRSHLVVHHRIHTGLKPFECKDCGKCFSRSSHLYSHQRTHTGEKPYECHDCGKSFSQSSALIVHQRIHTGEKPYECCQCGKAFIRKNDLIKHQRIHVGEETYKCNQCGIIFSQNSPFIVHQIAHTGEQFLTCNQCGTALVNTSNLIGYQTNHIRENAY

3D Structural Models

Domain & Motif Annotations

Zinc Finger

206..232; C2H2-type 1; atypical; 265..287; C2H2-type 2; 293..315; C2H2-type 3; 321..343; C2H2-type 4; 349..371; C2H2-type 5; 377..399; C2H2-type 6; 405..427; C2H2-type 7; 433..455; C2H2-type 8; 461..483; C2H2-type 9; 489..511; C2H2-type 10; 517..539; C2H2-type 11; atypical

Domain (FT)

14..85; KRAB

Protein Families

Krueppel C2H2-type zinc-finger protein family

Sequence Similarities

Belongs to the krueppel C2H2-type zinc-finger protein family.

Clinical Relevance

Antibody

HPA003204

Interaction Protein

ENSG00000130726

Interaction Count

Interaction Dataset

intact_biogrid