Protein detail

FGFR2

Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)

Protein symbol
FGFR2
UniProt ID
P21802
EVMP score
0.25
Frequency
1
Transmembrane count
1
Protein classification
Cancer-related genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteinsRAS pathway related proteins
Basic Information
Protein Names
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Protein Class
Cancer-related genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteinsRAS pathway related proteins
Protein Function
  • Cancer-related genes:Mutational cancer driver genes
  • Human disease related genes:Cancers:Cancers of the digestive system
  • Predicted intracellular proteins
  • Human disease related genes:Congenital malformations:Congenital malformations of the musculoskeletal system
  • ENZYME proteins:Transferases
  • Cancer-related genes:Mutated cancer genes
  • CD markers
  • RAS pathway related proteins
  • Enzymes
  • Cancer-related genes:Candidate cancer biomarkers
  • Predicted secreted proteins
  • Human disease related genes:Congenital malformations:Other congenital malformations
  • Kinases:Tyr protein kinases
  • Disease related genes
  • FDA approved drug targets:Small molecule drugs
  • FDA approved drug targets:Biotech drugs
Transmembrane
378..398; Helical
Transmembrane Count
1
Ensembl
ENSG00000066468
Entrez Gene Symbol
FGFR2
Gene Synonym
BEKCD332CEK3CFD1ECT1JWSK-SAMKGFRTK14TK25
Gene Description
Fibroblast growth factor receptor 2
Chromosome
10
Position
121478332-121598458
Frequency
1
EVMP Score
0.25
Fluorescence & Localization
Tissue SpecificbrainCell SpecificBrain excitatory neuronsBlood Cell Specificplasmacytoid DC
Function & Pathway
Protein Function
  • Cancer-related genes:Mutational cancer driver genes
  • Human disease related genes:Cancers:Cancers of the digestive system
  • Predicted intracellular proteins
  • Human disease related genes:Congenital malformations:Congenital malformations of the musculoskeletal system
  • ENZYME proteins:Transferases
  • Cancer-related genes:Mutated cancer genes
  • CD markers
  • RAS pathway related proteins
  • Enzymes
  • Cancer-related genes:Candidate cancer biomarkers
  • Predicted secreted proteins
  • Human disease related genes:Congenital malformations:Other congenital malformations
  • Kinases:Tyr protein kinases
  • Disease related genes
  • FDA approved drug targets:Small molecule drugs
  • FDA approved drug targets:Biotech drugs
Cellular Component
Molecular Function
Biological Process
KEGG
Reactome
Canonical Pathways
  • M56 Pid lpa4 pathway
  • M8 Pid endothelin pathway
  • M15 Pid lysophospholipid pathway
Mediation Categories
Clinical-translation mediationFusion and delivery mediationImmune mediationReceptor-signaling mediation
Relations & Evidence

Enzyme-Mediated Modification

5 records.

Substrate Gene SymbolEnzyme Gene SymbolEnzyme UniProt IDResidue TypeResidue OffsetModificationDatabaseReferences
FGFR2PRKCEQ02156S782phosphorylationSIGNOR_ProtMapperSIGNORProtMapperSIGNOR:23564461ProtMapper:23564461
FGFR2MAPK3P27361S780phosphorylationPhosphoSite
FGFR2MAPK1P28482S780phosphorylationPhosphoSite
FGFR2FGF2P09038S780phosphorylationREACH_ProtMapperProtMapperProtMapper:18332103
FGFR2FGFR1P11362Y769phosphorylationKEAKEA:17570479

Ligand-Receptor Signaling

61 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptor_tyrosine_kinases_rtkreceptorHPMRNoYesYesYesNo
fgrreceptorHPMRNoYesYesYesNo
kinasereceptorSurfaceomeNoYesYesYesNo
fgfrreceptorSurfaceomeNoYesYesYesNo
growth_factorreceptorICELLNETNoYesYesYesNo
growth_factor_fgf_familyreceptorICELLNETNoYesYesYesNo
receptorreceptorOmniPathNoYesYesYesNo
extracellularextracellularHPMRNoNoYesYesNo
extracellularextracellularLOCATENoNoYesYesNo
extracellularextracellularOmniPathNoNoYesYesNo
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Regulatory Interaction Network

20 records.

Source Protein SymbolSource UniProt IDTarget Protein SymbolTarget UniProt IDIs DirectedIs StimulationIs InhibitionDatabaseReferences
FGF1P05230FGFR2P21802YesYesNoiTALKICELLNETSIGNORHINTSignaLink3DIPLit-BM-17CellChatDBHPRD_LRdbDLRP_CellinkertalklrHPRDIntActDLRP_talklrWangRamilowski2015CellPhoneDBHPRD_talklrBioGRIDCellinkerSTRING_talklrCellCallCellTalkDBFantom5_LRdbconnectomeDB2020SPIKE_LCLRdbHINT:11714710Cellinker:25772309HINT:7499435Lit-BM-17:11714710HINT:1697263HPRD:11069186Lit-BM-17:10339576SPIKE_LC:17145710Cellinker:14732692Lit-BM-17:11069186HINT:10618369HPRD:14732692HINT:22955284DIP:8663044IntAct:25241761SignaLink3:8576175ICELLNET:25772309Lit-BM-17:23597563SIGNOR:10618369BioGRID:10618369connectomeDB2020:14732692Lit-BM-17:8663044SignaLink3:10618369connectomeDB2020:11069186CellTalkDB:16597617Cellinker:11069186Cellinker:10618369HINT:11069186HPRD:10618369DIP:10339576HINT:8576175Lit-BM-17:8576175HINT:22057274SignaLink3:23331499DIP:10618369IntAct:10618369HINT:33961781SignaLink3:21071413DIP:11069186connectomeDB2020:10618369SPIKE_LC:10618369Lit-BM-17:25241761Lit-BM-17:10618369HINT:23597563LRdb:16597617
FGF2P09038FGFR2P21802YesYesNoiTALKICELLNETSIGNORProtMapperHINTSignaLink3Lit-BM-17HPMR_talklrHPMRCellChatDBDLRP_CellinkertalklrCui2007IntActDLRP_talklrWangRamilowski2015HPMR_LRdbCellPhoneDBCellinkerREACH_ProtMapperSTRING_talklrCellCallCellTalkDBFantom5_LRdbHPMR_CellinkerconnectomeDB2020SPIKE_LCLRdbCellinker:25772309HINT:1697263SPIKE_LC:17145710Lit-BM-17:11121055HPMR:8663044ProtMapper:18332103IntAct:11390973SIGNOR:7687739HINT:11390973Lit-BM-17:17981115SIGNOR:11390973ICELLNET:25772309Lit-BM-17:11390973CellTalkDB:16597617HINT:10830168IntAct:10830168Lit-BM-17:26267536SPIKE_LC:17981115SignaLink3:23331499HINT:33961781Cellinker:8663044SignaLink3:8663044LRdb:16597617Lit-BM-17:10950949connectomeDB2020:8663044
FGF3P11487FGFR2P21802YesYesNoiTALKICELLNETSIGNORSignaLink3DIPHPMR_talklrCellChatDBHPRD_LRdbDLRP_CellinkertalklrHPRDDLRP_talklrWangRamilowski2015HPMR_LRdbCellPhoneDBHPRD_talklrCellinkerSTRING_talklrCellCallCellTalkDBFantom5_LRdbHPMR_CellinkerconnectomeDB2020LRdbconnectomeDB2020:7592624CellTalkDB:16597617Cellinker:25772309DIP:8663044Cellinker:7592624ICELLNET:25772309SIGNOR:8663044HPRD:8663044SignaLink3:23331499Cellinker:16597617SignaLink3:8663044LRdb:16597617Cellinker:8663044connectomeDB2020:8663044
FGF4P08620FGFR2P21802YesYesNoiTALKICELLNETSIGNORSignaLink3HPMR_talklrCellChatDBHPRD_LRdbDLRP_CellinkertalklrHPRDDLRP_talklrWangRamilowski2015HPMR_LRdbHPRD_talklrCellinkerSTRING_talklrCellCallCellTalkDBFantom5_LRdbHPMR_CellinkerconnectomeDB2020LRdbCellTalkDB:16597617Cellinker:25772309Cellinker:11486033ICELLNET:25772309SIGNOR:8663044HPRD:8663044connectomeDB2020:11486033SignaLink3:23331499Cellinker:16597617SignaLink3:8663044LRdb:16597617Cellinker:8663044connectomeDB2020:8663044
FGF7P21781FGFR2P21802YesYesNoiTALKICELLNETHINTSignaLink3DIPLit-BM-17HPMR_talklrCellChatDBHPRD_LRdbDLRP_CellinkertalklrHPRDDLRP_talklrWangRamilowski2015HPMR_LRdbCellPhoneDBHPRD_talklrCellinkerSTRING_talklrCellCallCellTalkDBFantom5_LRdbHPMR_CellinkerconnectomeDB2020LRdbDIP:10950949HINT:11714710Cellinker:25772309DIP:11121055HINT:7499435Lit-BM-17:11714710Lit-BM-17:10339576Cellinker:27192911Lit-BM-17:11121055SignaLink3:9582367connectomeDB2020:12591959DIP:8663044ICELLNET:25772309HPRD:7687739Lit-BM-17:8663044CellTalkDB:16597617Lit-BM-17:9582367Lit-BM-17:1309608connectomeDB2020:7687739DIP:10339576SignaLink3:23331499Cellinker:12591959Cellinker:7687739SignaLink3:21071413HINT:9582367Cellinker:16597617SignaLink3:8663044LRdb:16597617Lit-BM-17:10950949
FGF8P55075FGFR2P21802YesYesNoiTALKICELLNETHINTSignaLink3HPMR_talklrCellChatDBHPRD_LRdbDLRP_CellinkertalklrHPRDDLRP_talklrWangRamilowski2015HPMR_LRdbHPRD_talklrCellinkerSTRING_talklrCellCallCellTalkDBFantom5_LRdbHPMR_CellinkerconnectomeDB2020LRdbCellTalkDB:16597617Cellinker:10751172Cellinker:25772309ICELLNET:25772309HPRD:8663044HINT:16384934connectomeDB2020:8663044SignaLink3:23331499SignaLink3:8663044connectomeDB2020:10751172LRdb:16597617Cellinker:8663044HPRD:10751172
FGF10O15520FGFR2P21802YesYesNoiTALKICELLNETSIGNORHINTSignaLink3Lit-BM-17HPMR_talklrCellChatDBHPRD_LRdbDLRP_CellinkertalklrHPRDDLRP_talklrWangRamilowski2015HPMR_LRdbCellPhoneDBHPRD_talklrCellinkerSTRING_talklrCellCallCellTalkDBFantom5_LRdbHPMR_CellinkerconnectomeDB2020SPIKE_LCLRdbCellinker:25772309Lit-BM-17:10339576SPIKE_LC:17145710SignaLink3:9582367connectomeDB2020:12591959Cellinker:9582367ICELLNET:25772309SIGNOR:9582367SIGNOR:8663044HPRD:9582367CellTalkDB:16597617Lit-BM-17:9582367connectomeDB2020:9582367SignaLink3:23331499Cellinker:12591959SignaLink3:21071413SPIKE_LC:12591959Lit-BM-17:25241761HINT:9582367HINT:12591959Cellinker:16597617SignaLink3:8663044Lit-BM-17:12591959LRdb:16597617
FGFR2P21802GRAPQ13588YesYesNoSignaLink3SignaLink3:19735729SignaLink3:23331499
FGF6P10767FGFR2P21802YesYesNoiTALKICELLNETSIGNORSignaLink3CellChatDBHPRD_LRdbDLRP_CellinkertalklrHPRDDLRP_talklrWangRamilowski2015HPRD_talklrCellinkerSTRING_talklrCellCallCellTalkDBFantom5_LRdbconnectomeDB2020LRdbCellTalkDB:16597617Cellinker:25772309ICELLNET:25772309SIGNOR:8663044HPRD:8663044SignaLink3:23331499Cellinker:16597617SignaLink3:8663044LRdb:16597617Cellinker:8663044connectomeDB2020:8663044
FGF17O60258FGFR2P21802YesYesNoiTALKICELLNETSIGNORSignaLink3CellChatDBHPRD_LRdbDLRP_CellinkertalklrHPRDDLRP_talklrWangRamilowski2015HPRD_talklrCellinkerCellCallCellTalkDBFantom5_LRdbconnectomeDB2020LRdbCellTalkDB:16597617Cellinker:10751172Cellinker:25772309ICELLNET:25772309SIGNOR:8663044SignaLink3:23331499SignaLink3:8663044connectomeDB2020:10751172LRdb:16597617HPRD:10751172
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Protein Complex Composition

6 records.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
FGF10FGFR2O15520P218021:1PDBPDB:1nun
FGF1FGFR2P05230P218022:2PDBPDB:4j23PDB:1e0oPDB:3ojmPDB:3cu1PDB:3oj2PDB:1djs
FGF2FGFR2P09038P218024:4PDBPDB:1ii4PDB:1ev2PDB:1iil
FGFR2P218022PDBPDB:5ugxPDB:6lvlPDB:8e1xPDB:7ozyPDB:2pzpPDB:8stgPDB:4j96PDB:4j99PDB:2pz5PDB:8w38PDB:2psqPDB:5uhnPDB:7kiePDB:8u1fPDB:6v6qPDB:4wv1PDB:4j97PDB:3euuPDB:4j95PDB:3darPDB:9u3nPDB:8h75PDB:8w3bPDB:3ri1PDB:3b2tPDB:8w3dPDB:6lvkPDB:5uglPDB:8swePDB:2py3PDB:2pvfPDB:8w2xPDB:6agxPDB:7kiaPDB:2pzrPDB:2pvyPDB:2pwlPDB:5ui0PDB:4j98PDB:2q0b
FGF8FGFR2P21802P550752:2PDBPDB:2fdb
C8orf74FGFR2MORN2P21802Q502X0Q6P0470:0:0hu.MAP

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationMass spectrometry127863537
Sequence, Structure & Domains

Sequences

Length
821
Mass
92,025
Sequence
MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT
Alternative Products
Event=Alternative splicing; Named isoforms=17; Name=1; Synonyms=BEK, FGFR2IIIc; IsoId=P21802-1; Sequence=Displayed; Name=2; Synonyms=Short; IsoId=P21802-2; Sequence=VSP_002978; Name=3; Synonyms=BFR-1, FGFR2IIIb, KGFR; IsoId=P21802-3; Sequence=VSP_002969, VSP_002970, VSP_002971, VSP_002972; Name=4; Synonyms=K-sam; IsoId=P21802-4; Sequence=VSP_002964, VSP_002969, VSP_002970, VSP_002971, VSP_002972, VSP_002975, VSP_002976; Name=5; Synonyms=K-sam-I, BEK, IgIIIc; IsoId=P21802-5; Sequence=VSP_002975; Name=6; Synonyms=K-sam-IIC2; IsoId=P21802-6; Sequence=VSP_002975, VSP_002984; Name=7; Synonyms=K-sam-IIC3; IsoId=P21802-8; Sequence=VSP_002975, VSP_002978; Name=8; Synonyms=K-sam-IV, Soluble KGFR; IsoId=P21802-14; Sequence=VSP_002965, VSP_002966; Name=9; Synonyms=K-sam-III; IsoId=P21802-15; Sequence=VSP_002968; Name=10; Synonyms=TK14; IsoId=P21802-16; Sequence=VSP_002967, VSP_002975; Name=11; IsoId=P21802-17; Sequence=VSP_002969, VSP_002970, VSP_002971, VSP_002972, VSP_002978; Name=12; Synonyms=K-sam-IIC1, KGFR, IgIIIb; IsoId=P21802-18; Sequence=VSP_002969, VSP_002970, VSP_002971, VSP_002972, VSP_002975; Name=13; Synonyms=Soluble KGFR; IsoId=P21802-19; Sequence=VSP_002969, VSP_002970, VSP_002971, VSP_002972, VSP_002973, VSP_002974; Name=14; IsoId=P21802-20; Sequence=VSP_019608, VSP_019609; Name=15; IsoId=P21802-21; Sequence=VSP_002964, VSP_041915; Name=16; IsoId=P21802-22; Sequence=VSP_002964, VSP_002969, VSP_002970, VSP_002971, VSP_002972, VSP_002978; Name=17; IsoId=P21802-23; Sequence=VSP_041914
Alternative Sequence
37..152; EPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKR -> G (in isoform 14); 37..125; Missing (in isoform 4, isoform 15 and isoform 16); 250..361; Missing (in isoform 17); 250..254; ERSPH -> GSQGL (in isoform 8); 255..821; Missing (in isoform 8); 313; K -> KVTK (in isoform 10); 314..429; Missing (in isoform 9); 314..330; AAGVNTTDKEIEVLYIR -> HSGINSSNAEVLALF (in isoform 3, isoform 4, isoform 11, isoform 12, isoform 13 and isoform 16); 334..335; FE -> EA (in isoform 3, isoform 4, isoform 11, isoform 12, isoform 13 and isoform 16); 341..353; TCLAGNSIGISFH -> ICKVSNYIGQANQ (in isoform 3, isoform 4, isoform 11, isoform 12, isoform 13 and isoform 16); 361; P -> PKQQ (in isoform 3, isoform 4, isoform 11, isoform 12, isoform 13 and isoform 16); 362..365; APGR -> GRRC (in isoform 13); 366..821; Missing (in isoform 13); 428..429; Missing (in isoform 4, isoform 5, isoform 6, isoform 7, isoform 10 and isoform 12); 429..430; Missing (in isoform 14); 761..821; LTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT -> PPNPSLMSIFRK (in isoform 4); 768..821; EYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT -> I (in isoform 2, isoform 7, isoform 11 and isoform 16); 769..821; YLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT -> EKKVSGAVDCHKPPCNPSHLPCVLAVDQ (in isoform 15); 778..821; QYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT -> PYSPCYPDPR (in isoform 6)

3D Structural Models

Turn
159..162; 463..465; 472..474; 490..492; 585..588; 636..638; 652..654; 659..662
Helix
200..202; 211..213; 223..225; 321..323; 334..336; 478..480; 525..541; 572..577; 590..592; 594..596; 600..619; 629..631; 645..647; 667..669; 672..677; 682..697; 709..718; 730..739; 744..746; 750..764
Beta Strand
152..157; 166..170; 175..178; 181..185; 188..193; 203..205; 208..210; 215..218; 227..235; 238..249; 266..269; 274..277; 287..293; 296..298; 299..301; 303..305; 309..314; 315..319; 324..327; 338..346; 349..360; 481..489; 494..500; 504..506; 513..518; 550..554; 556..558; 561..565; 568..571; 632..634; 640..642; 655..658; 664..666; 726..728
3D Structure
NMR spectroscopy (1); X-ray crystallography (56)

Domain & Motif Annotations

Compositional Bias
131..144; Acidic residues
Domain (CC)
The second and third Ig-like domains directly interact with fibroblast growth factors (FGF) and heparan sulfate proteoglycans. Alternative splicing events affecting the third Ig-like domain are crucial for ligand selectivity.
Domain (FT)
25..125; Ig-like C2-type 1; 154..247; Ig-like C2-type 2; 256..358; Ig-like C2-type 3; 481..770; Protein kinase
Region
131..151; Disordered; 161..178; Heparin-binding
Protein Families
  • Protein kinase superfamily
  • Tyr protein kinase family
  • Fibroblast growth factor receptor subfamily
Sequence Similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
Clinical Relevance
Disease Involvement
Cancer-related genesCraniosynostosisDisease variantEctodermal dysplasiaFDA approved drug targetsIntellectual disabilityLacrimo-auriculo-dento-digital syndromeProto-oncogene
Related Diseases
Alzheimer diseaseBladder cancerBreast cancerHepatitis virus infectionLiver cancerMyeloproliferative neoplasmOral mucositisPeriodontal diseaseRetina cancerSolid tumour/cancerStomach cancer
Biomarker
Phase 1/2; Phase 2; Approved; Phase 3; Terminated; Phase 1
Drug Targets
FDA approved drug targets
Drugs
S-49076INAVOLISIBXL228NINTEDANIB ESYLATEDOVITINIBFEXAGRATINIBNULLOLVEREMBATINIBALPELISIBNAVITOCLAXBRIVANIBDERAZANTINIBPD173074ORANTINIBPALIFERMINBEMARITUZUMABRABEPRAZOLETG100-801PEGINTERFERON ALFA-2AINFIGRATINIBHMPL-453MUPARFOSTATFUTIBATINIBMK-2461FGFR INHIBITOR CPL304110RG-1530SUNITINIBERDAFITINIBCETRELIMABAKT INHIBITOR MK2206TINENGOTINIBZOTATIFINVEMURAFENIBFGFR INHIBITOR DEBIO 1347TASURGRATINIBPONATINIBENMD-2076TRAFERMINPICTILISIBENMD-981693REGORAFENIBKIN-3248BUPARLISIBMASITINIBPAZOPANIBAEE-788ABT-737APRUTUMAB IXADOTINZOLIGRATINIBXL999LY2874455FPA144LUCITANIBTRAMETINIB DIMETHYL SULFOXIDEPEMIGATINIBINFIGRATINIB PHOSPHATEAZD-4547FULVESTRANTVARGATEFFGFR1/2/3 INHIBITOR TYRA-200FP-1039THALIDOMIDEMEK INHIBITOR RO4987655LENVATINIBSELUMETINIBROGARATINIBALOFANIBAPRUTUMABFGFR/CSF-1R INHIBITOR 3D185LY-2874455LIRAFUGRATINIBOXALIPLATINPRN1371ODM-203CP-459632AVUTOMETINIBTRABECTEDINFGF RECEPTOR ANTAGONIST HGS1036TEMUTERKIBCEDIRANIBXL-999GUNAGRATINIBLEUCOVORIN CALCIUMPHA-665752BRIVANIB ALANINATEFLUOROURACIL
Antibody
CAB010886HPA035305
Interaction Protein
ENSG00000070193ENSG00000077782ENSG00000113578ENSG00000138685ENSG00000179295
Interaction Count
5
Interaction Dataset
intact_biogrid