Protein detail
CD1C
T-cell surface glycoprotein CD1c (CD antigen CD1c)
Entry name CD1C | UniProt ID | EVMP confidence score 0.25 |
Supporting publications (n) 1 | Transmembrane count 1 | Protein classification |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information8
Protein Names
T-cell surface glycoprotein CD1c (CD antigen CD1c)
Protein Function (2)
- CD markers
- Predicted intracellular proteins
Transmembrane
303..323; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Supporting publications (n)
1
EVMP confidence score
0.25
Fluorescence & Localization6
Tissue SpecificbrainCell SpecificEndometrial ciliated cellsSingle-Nuclei Brain Specificependymal cellBlood Cell SpecificgdT-cellBlood Lineage SpecificT-cells
Function & Pathway7
Protein Function (2)
- CD markers
- Predicted intracellular proteins
Cellular Component (8)
Molecular Function (5)
Biological Process (3)
Reactome (2)
Mediation Categories (2)
Fusion and delivery mediationImmune mediation
Relations & Evidence35
Ligand-Receptor Signaling (34)
34 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | Cellinker | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | Membranome | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | CSPA | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | OmniPath | No | No | No | Yes | No |
| cell_surface | cell_surface | Surfaceome | No | No | No | Yes | No |
| cell_surface | cell_surface | OmniPath | No | No | No | Yes | No |
| receptor | receptor | Cellinker | No | Yes | No | Yes | No |
| receptor | receptor | Almen2009 | No | Yes | No | Yes | No |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Protein Organic Solvent Precipitation | Mass spectrometry | 1 | 32384937 |
Sequence, Structure & Domains9
Sequences
Length
333
Mass
37,654
Sequence
MLFLQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDSESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGCELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHHFSMNWIALVVIVPLVILIVLVLWFKKHCSYQDIL
3D Structural Models
Turn
60..63; 70..75
Helix
78..103; 107..109; 157..168; 171..182; 184..200; 285..287
Beta Strand
25..38; 41..50; 53..59; 64..67; 111..123; 124..126; 129..136; 139..144; 146..151; 153..155; 207..214; 221..233; 235..241; 244..246; 249..251; 262..264; 278..284; 292..295
3D Structure
X-ray crystallography (5)
Domain & Motif Annotations
Motif
329..332; Internalization signal
Domain (FT)
206..296; Ig-like
Supporting Publications1
| PMID | Title | Abstract |
|---|---|---|
| 38716512 | Assessment of urine sample collection and processing variables for extracellular vesicle-based proteomics. | No abstract available |