Protein detail
CD151
CD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (Tetraspanin-24) (Tspan-24) (CD antigen CD151)
Protein symbol CD151 | UniProt ID | EVMP score 0.25 |
Frequency 1 | Transmembrane count 4 | Protein classification Blood group antigen proteinsCD markersDisease related genesHuman disease related genesPotential drug targetsPredicted membrane proteinsTransporters |
Basic Information
Protein Names
CD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (Tetraspanin-24) (Tspan-24) (CD antigen CD151)
Protein Class
Blood group antigen proteinsCD markersDisease related genesHuman disease related genesPotential drug targetsPredicted membrane proteinsTransporters
Protein Function
- Human disease related genes:Urinary system diseases:Kidney diseases
- Blood group antigen proteins
- CD markers
- Potential drug targets
- Human disease related genes:Skin diseases:Skin and soft tissue diseases
- Human disease related genes:Congenital malformations:Congenital malformations of skin
- Transporters:Accessory Factors Involved in Transport
- Disease related genes
Transmembrane
19..39; Helical; 58..78; Helical; 92..112; Helical; 222..242; Helical
Transmembrane Count
4
Ensembl
Entrez Gene Symbol
Gene Synonym
PETA-3RAPHSFA-1TSPAN24
Gene Description
CD151 molecule (Raph blood group)
Chromosome
11
Position
832887-839831
Frequency
1
EVMP Score
0.25
Fluorescence & Localization
Tissue SpecificretinaCell SpecificCone photoreceptor cells
Function & Pathway
Protein Function
- Human disease related genes:Urinary system diseases:Kidney diseases
- Blood group antigen proteins
- CD markers
- Potential drug targets
- Human disease related genes:Skin diseases:Skin and soft tissue diseases
- Human disease related genes:Congenital malformations:Congenital malformations of skin
- Transporters:Accessory Factors Involved in Transport
- Disease related genes
Cellular Component
Molecular Function
Biological Process
Reactome
Mediation Categories
Adhesion and uptake mediationImmune mediationReceptor-signaling mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
29 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | Cellinker | No | No | No | Yes | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | HPMR | No | No | No | Yes | No |
| plasma_membrane_transmembrane | plasma_membrane_transmembrane | OmniPath | No | No | No | Yes | No |
| cell_surface | cell_surface | Surfaceome | No | No | No | Yes | No |
| cell_surface | cell_surface | connectomeDB2020 | No | No | No | Yes | No |
| cell_surface | cell_surface | OmniPath | No | No | No | Yes | No |
| transmembrane | transmembrane_predicted | Phobius | No | No | No | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 1 | 37438638 |
Sequence, Structure & Domains
Sequences
Length
253
Mass
28,295
Sequence
MGEFNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSLKLEHY
3D Structural Models
Domain & Motif Annotations
Protein Families
Tetraspanin (TM4SF) family
Sequence Similarities
Belongs to the tetraspanin (TM4SF) family.