Protein detail
RPIA
Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase)
Entry name RPIA | UniProt ID | EVMP score 0.38 |
Frequency 4 | Transmembrane count | Protein classification Disease related genesEnzymesHuman disease related genesMetabolic proteinsPlasma proteinsPotential drug targetsPredicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase)
Protein Class
Disease related genesEnzymesHuman disease related genesMetabolic proteinsPlasma proteinsPotential drug targetsPredicted intracellular proteins
Protein Function
- ENZYME proteins:Isomerase
- Predicted intracellular proteins
- Human disease related genes:Congenital disorders of metabolism:Congenital disorders of nucleotide metabolism
- Potential drug targets
- Enzymes
- Disease related genes
Ensembl
Entrez Gene Symbol
Gene Description
Ribose 5-phosphate isomerase A
Chromosome
2
Position
88691673-88750929
Frequency
4
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecifictestisCell SpecificChoroid plexus epithelial cells
Function & Pathway
Protein Function
- ENZYME proteins:Isomerase
- Predicted intracellular proteins
- Human disease related genes:Congenital disorders of metabolism:Congenital disorders of nucleotide metabolism
- Potential drug targets
- Enzymes
- Disease related genes
Cellular Component
Molecular Function
Biological Process
KEGG
Reactome
Mediation Categories
Clinical-translation mediationMetabolism mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
3 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Protein Organic Solvent Precipitation | Mass spectrometry | 1 | 32384937 |
Sequence, Structure & Domains
Sequences
Length
311
Mass
33,269
Sequence
MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNSWDLPGSHVRLPGRAQSGTRGGAGNTSTSCGDSNSICPAPSTMSKAEEAKKLAGRAAVENHVRNNQVLGIGSGSTIVHAVQRIAERVKQENLNLVCIPTSFQARQLILQYGLTLSDLDRHPEIDLAIDGADEVDADLNLIKGGGGCLTQEKIVAGYASRFIVIADFRKDSKNLGDQWHKGIPIEVIPMAYVPVSRAVSQKFGGVVELRMAVNKAGPVVTDNGNFILDWKFDRVHKWSEVNTAIKMIPGVVDTGLFINMAERVYFGMQDGSVNMREKPFC
3D Structural Models
Domain & Motif Annotations
Compositional Bias
22..32; Gly residues; 57..67; Polar residues
Region
22..67; Disordered
Protein Families
Ribose 5-phosphate isomerase family
Sequence Similarities
Belongs to the ribose 5-phosphate isomerase family.