Protein detail

PLXA3

Plexin-A3 (Plexin-4) (Semaphorin receptor SEX)

Entry name PLXA3	UniProt ID P51805	EVMP confidence score 0.40
Supporting publications (n) 2	Transmembrane count 1	Protein classification

Basic Information

Protein Names

Plexin-A3 (Plexin-4) (Semaphorin receptor SEX)

Transmembrane

1221..1241; Helical

Transmembrane Count

Ensembl

ENSG00000130827

Entrez Gene Symbol

PLXNA3

Supporting publications (n)

EVMP confidence score

0.40

Function & Pathway

Cellular Component (2)

Molecular Function (2)

Biological Process (3)

KEGG (2)

Reactome (5)

Canonical Pathways

M86 Pid arf6 pathway

Mediation Categories (2)

Adhesion and uptake mediationReceptor-signaling mediation

Relations & Evidence57

Ligand-Receptor Signaling (52)

52 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
transmembrane	transmembrane_predicted	Phobius				Yes
transmembrane_phobius	transmembrane_predicted	Almen2009				Yes

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Protein Complex Composition (5)

5 records.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
PLXNA3-RANBPM complex	PLXNA3 RANBP9	P51805 Q96S59	1:1	CompleatCORUM	Compleat:HC1031CORUM:5759	16672672
	FAM234B GALNT13 MBTPS1 PLXNA3 PTPRU	A2RU67 P51805 Q14703 Q8IUC8 Q92729	0:0:0:0:0	hu.MAP
	CHST10 CNTNAP3 ENTPD6 GALNT13 LRIG1 PLXNA3 PTPRU	O43529 O75354 P51805 Q8IUC8 Q92729 Q96JA1 Q9BZ76	0:0:0:0:0:0:0	hu.MAP
	KNTC1 MLH1 PLXNA3 PMS1 PMS2	P40692 P50748 P51805 P54277 P54278	0:0:0:0:0	hu.MAP2
	GALNT13 LRIG1 PLXNA3	P51805 Q8IUC8 Q96JA1	0:0:0	hu.MAP

Sequence, Structure & Domains

Sequences

Length

1,871

Mass

207,717

Sequence

MPSVCLLLLLFLAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGVIVEQGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTPMQINGNFCGLVLNQPLGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASAPHGFAEELSKCVQVRVRPNNVSVTSPGVQLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPEILPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRFNCGWCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVGENLGLLSREVGLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYRGIETTNTCQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSLTVSDTQLLCDSPSQTGRQPVMVLVGGLEFWLGTLHISAERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTPPNVEKALRLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNCDSITQAKDKLLDTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSLVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHLVKNHDHADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISLVSSDS

Domain & Motif Annotations

Domain (FT)

20..488; Sema; 840..933; IPT/TIG 1; 935..1020; IPT/TIG 2; 1023..1122; IPT/TIG 3; 1125..1211; IPT/TIG 4

Protein Families

Plexin family

Sequence Similarities

Belongs to the plexin family.

Supporting Publications2

PMID	Title	Related sentences
40091455	Potential Role of Menstrual Fluid-Derived Small Extracellular Vesicle Proteins in Endometriosis Pathogenesiss.	No related sentences available
40784529	Serum-derived exosome proteomics unveils the distinct and adjustable nature of the dampness constitution in traditional Chinese medicine.	No related sentences available