Protein detail

ARL4C

ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK)

Protein symbol ARL4C	UniProt ID P56559	EVMP score 0.50
Frequency 5	Transmembrane count	Protein classification Predicted intracellular proteins

Basic Information

Protein Names

ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK)

Protein Class

Predicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000188042

Entrez Gene Symbol

ARL4C

Gene Synonym

ARL7LAK

Gene Description

ADP ribosylation factor like GTPase 4C

Chromosome

Position

234493041-234497081

Frequency

EVMP Score

0.50

Fluorescence & Localization

Cell SpecificMonocyte progenitors

Function & Pathway

Protein Function

Predicted intracellular proteins

Cellular Component

Molecular Function

Biological Process

Reactome

Mediation Categories

Receptor-signaling mediation

Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

6 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
intracellular	intracellular	ComPPI	No	No	No	No	No
intracellular	intracellular	GO_Intercell	No	No	No	No	No
intracellular	intracellular	UniProt_location	No	No	No	No	No
intracellular	intracellular	OmniPath	No	No	No	No	No
plasma_membrane	plasma_membrane	UniProt_location	No	No	No	No	No
plasma_membrane	plasma_membrane	OmniPath	No	No	No	No	No

Regulatory Interaction Network

0 records.

Protein Complex Composition

4 records.

Component Gene Symbols	Component UniProt ID	Stoichiometry	Database
ARL4C FBXO33 GADD45A RAD51B RAD51D RGS12 XRCC2	O14924 O15315 O43543 O75771 P24522 P56559 Q7Z6M2	0:0:0:0:0:0:0	hu.MAP2
ARL4C DCUN1D4 FBXO33 GADD45A RAD51B RAD51D RGS12 XRCC2	O14924 O15315 O43543 O75771 P24522 P56559 Q7Z6M2 Q92564	0:0:0:0:0:0:0:0	hu.MAP2
ARL4C DCUN1D4 FBXO33 GADD45A RGS12	O14924 P24522 P56559 Q7Z6M2 Q92564	0:0:0:0:0	hu.MAP2
ARL4C DCUN1D4 FBXO33 GADD45A XRCC2	O43543 P24522 P56559 Q7Z6M2 Q92564	0:0:0:0:0	hu.MAP2

Isolation & Detection Technology

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationSize Exclusion Chromatography	Mass spectrometry	11	40465195 41068253 33592500 40940449 37563857 38917926 41307968 40840701 38207106 39207047 37926756

Sequence, Structure & Domains

Sequences

Length

192

Mass

21,487

Sequence

MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIKLSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELIPATTYHVQPACAIIGEGLTEGMDKLYEMILKRRKSLKQKKKR

Alternative Products

Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P56559-1; Sequence=Displayed; Name=2; IsoId=P56559-2; Sequence=VSP_055120

Alternative Sequence

192; R -> RTGDLRSCEV (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Protein Families

Small GTPase superfamily
Arf family

Sequence Similarities

Belongs to the small GTPase superfamily. Arf family.

Clinical Relevance

Antibody

HPA028927