Protein detail
RGS8
Regulator of G-protein signaling 8 (RGS8)
Entry name RGS8 | UniProt ID | EVMP confidence score 0.40 |
Supporting publications (n) 2 | Transmembrane count | Protein classification Predicted intracellular proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Regulator of G-protein signaling 8 (RGS8)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
MGC119067MGC119068MGC119069
Gene Description
Regulator of G protein signaling 8
Chromosome
1
Position
182641816-182684587
Supporting publications (n)
2
EVMP confidence score
0.40
Fluorescence & Localization
Cell SpecificMyonuclei
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (7)
Molecular Function (3)
Biological Process (3)
Mediation Categories
Receptor-signaling mediation
Relations & Evidence12
Ligand-Receptor Signaling (9)
9 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | OmniPath | Yes | ||||
| intracellular | intracellular | LOCATE | |||||
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | UniProt_location | |||||
| intracellular | intracellular | OmniPath | |||||
| plasma_membrane | plasma_membrane | UniProt_location | |||||
| plasma_membrane | plasma_membrane | OmniPath | |||||
| receptor | receptor | scConnect | Yes |
Protein Complex Composition (2)
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential Ultracentrifugation | Mass spectrometry | 1 | 39123364 |
Sequence, Structure & Domains
Sequences
Length
180
Mass
20,917
Sequence
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P57771-1; Sequence=Displayed; Name=2; IsoId=P57771-2; Sequence=VSP_036421
Alternative Sequence
1..9; MAALLMPRR -> MWNTLTRSLSDHPVGKDPQAMRTGQRQ (in isoform 2)
3D Structural Models
Turn
53..55; 140..143; 170..172
Helix
47..52; 57..61; 64..76; 81..92; 98..112; 125..134; 144..156; 158..163; 166..169
3D Structure
X-ray crystallography (3)
Domain & Motif Annotations
Domain (FT)
56..171; RGS
Supporting Publications2
| PMID | Title | Related sentences |
|---|---|---|
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No related sentences available |
| 40098346 | Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays. | No related sentences available |