Protein detail

RGS8

Regulator of G-protein signaling 8 (RGS8)

Protein symbol
RGS8
UniProt ID
EVMP score
0.50
Frequency
2
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Regulator of G-protein signaling 8 (RGS8)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
MGC119067MGC119068MGC119069
Gene Description
Regulator of G protein signaling 8
Chromosome
1
Position
182641816-182684587
Frequency
2
EVMP Score
0.50
Fluorescence & Localization
Cell SpecificMyonuclei
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

9 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptorreceptorOmniPathNoYesNoNoNo
intracellularintracellularLOCATENoNoNoNoNo
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo
plasma_membraneplasma_membraneUniProt_locationNoNoNoNoNo
plasma_membraneplasma_membraneOmniPathNoNoNoNoNo
receptorreceptorscConnectNoYesNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

2 records.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
GNAI3RGS8P08754P577712:2PDBPDB:2ode
INPP4ANXT2RGS8P57771Q96PE3Q9NPJ80:0:0hu.MAP2

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationMass spectrometry139123364
Sequence, Structure & Domains

Sequences

Length
180
Mass
20,917
Sequence
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P57771-1; Sequence=Displayed; Name=2; IsoId=P57771-2; Sequence=VSP_036421
Alternative Sequence
1..9; MAALLMPRR -> MWNTLTRSLSDHPVGKDPQAMRTGQRQ (in isoform 2)

3D Structural Models

Turn
53..55; 140..143; 170..172
Helix
47..52; 57..61; 64..76; 81..92; 98..112; 125..134; 144..156; 158..163; 166..169
3D Structure
X-ray crystallography (3)

Domain & Motif Annotations

Domain (FT)
56..171; RGS
Clinical Relevance
Drugs
Antibody