Protein detail

DJB13

DnaJ homolog subfamily B member 13 (Testis and spermatogenesis cell-related protein 6) (Testis spermatocyte apoptosis-related gene 6 protein) (Testis spermatogenesis apoptosis-related gene 3 protein) (Testis spermatogenesis apoptosis-related gene 6 protein)

Entry name
DJB13
UniProt ID
P59910
EVMP confidence score
0.38
Supporting publications (n)
1
Transmembrane count
Protein classification
Disease related genesHuman disease related genesPredicted intracellular proteins
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information11
Protein Names
DnaJ homolog subfamily B member 13 (Testis and spermatogenesis cell-related protein 6) (Testis spermatocyte apoptosis-related gene 6 protein) (Testis spermatogenesis apoptosis-related gene 3 protein) (Testis spermatogenesis apoptosis-related gene 6 protein)
Protein Class (3)
Disease related genesHuman disease related genesPredicted intracellular proteins
Protein Function (3)
  • Disease related genes
  • Human disease related genes:Respiratory diseases:Tracheobronchial diseases
  • Predicted intracellular proteins
Ensembl
ENSG00000187726
Entrez Gene Symbol
DNAJB13
Gene Synonym (2)
RSPH16ATSARG6
Gene Description
DnaJ heat shock protein family (Hsp40) member B13
Chromosome
11
Position
73951026-73970366
Supporting publications (n)
1
EVMP confidence score
0.38
Fluorescence & Localization4
Tissue Specificadrenal glandCell SpecificAdipocytesBlood Cell SpecificbasophilBlood Lineage Specificgranulocytes
Function & Pathway6
Protein Function (3)
  • Disease related genes
  • Human disease related genes:Respiratory diseases:Tracheobronchial diseases
  • Predicted intracellular proteins
Cellular Component (5)
Molecular Function (3)
Biological Process (3)
Canonical Pathways (2)
  • M257 Pid ephrinb rev pathway
  • M62 Pid ephb fwd pathway
Mediation Categories
Other mediation
Relations & Evidence3

Ligand-Receptor Signaling (3)

3 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo
Sequence, Structure & Domains7

Sequences

Length
316
Mass
36,118
Sequence
MGQDYYSVLGITRNSEDAQIKQAYRRLALKHHPLKSNEPSSAEIFRQIAEAYDVLSDPMKRGIYDKFGEEGLKGGIPLEFGSQTPWTTGYVFHGKPEKVFHEFFGGNNPFSEFFDAEGSEVDLNFGGLQGRGVKKQDPQVERDLYLSLEDLFFGCTKKIKISRRVLNEDGYSSTIKDKILTIDVKPGWRQGTRITFEKEGDQGPNIIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDDRLLNIPINDIIHPKYFKKVPGEGMPLPEDPTKKGDLFIFFDIQFPTRLTPQKKQMLRQALLT
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P59910-1; Sequence=Displayed; Name=2; Synonyms=TSARG5; IsoId=P59910-2; Sequence=VSP_008519, VSP_008520
Alternative Sequence
1..175; Missing (in isoform 2); 176..201; KDKILTIDVKPGWRQGTRITFEKEGD -> METSRGRNLAKVTRPTSPCHLLASPA (in isoform 2)

3D Structural Models

3D Structure
Electron microscopy (1)

Domain & Motif Annotations

Domain (FT)
4..68; J
Clinical Relevance2
Disease Involvement (3)
CiliopathyDisease variantPrimary ciliary dyskinesia
Antibody (2)
HPA052465HPA061330
Supporting Publications1
PMIDTitleAbstract
39066974The Proteomic Analysis of Chronic Migraine Exosomes Reveals Disease Patterns and Potential Biomarkers.These data revealed dysregulated proteins in plasma exosomes of CM, and the combination of plasma exosomal proteins RAP2B, AK1, BID, DAG1, PICALM, and PSMB2 could serve as a novel candidate biomarker for CM diagnosis.