Protein detail
BT3A2
Butyrophilin subfamily 3 member A2
Protein symbol BT3A2 | UniProt ID | EVMP score 0.38 |
Frequency | Transmembrane count 1 | Protein classification Predicted intracellular proteinsPredicted membrane proteins |
Basic Information
Protein Names
Butyrophilin subfamily 3 member A2
Protein Class
Predicted intracellular proteinsPredicted membrane proteins
Protein Function
Predicted intracellular proteins
Transmembrane
249..269; Helical
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Gene Synonym
3.2
Gene Description
Butyrophilin subfamily 3 member A2
Chromosome
6
Position
26365159-26378320
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificAstrocytesBlood Cell Specificnaive B-cell
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Fusion and delivery mediationImmune mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
30 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| receptor | receptor | GO_Intercell | No | Yes | No | Yes | No |
| butyrophilin | receptor | Almen2009 | No | Yes | No | Yes | No |
| receptor | receptor | OmniPath | No | Yes | No | Yes | No |
| extracellular | extracellular | DGIdb | No | No | No | Yes | No |
| extracellular | extracellular | OmniPath | No | No | No | Yes | No |
| butyrophilin | cell_surface_ligand | HGNC | Yes | No | No | Yes | No |
| cell_surface_ligand | cell_surface_ligand | OmniPath | Yes | No | No | Yes | No |
| cell_adhesion | cell_adhesion | Cellinker | Yes | Yes | No | Yes | No |
| adhesion | adhesion | OmniPath | Yes | Yes | No | Yes | No |
| cell_adhesion | cell_adhesion | OmniPath | Yes | Yes | No | Yes | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| PRotein Organic Solvent Precipitation；Differential Ultracentrifugation | Mass spectrometry | 1 | 32384937 |
Sequence, Structure & Domains
Sequences
Length
334
Mass
36,428
Sequence
MKMASSLAFLLLNFHVSLLLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSNLHVEVKGYEDGGIHLECRSTGWYPQPQIQWSNAKGENIPAVEAPVVADGVGLYEVAASVIMRGGSGEGVSCIIRNSLLGLEKTASISIADPFFRSAQPWIAALAGTLPILLLLLAGASYFLWRQQKEITALSSEIESEQEMKEMGYAATEREISLRESLQEELKRKKIQYLTRGEESSSDTNKSA
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=P78410-1; Sequence=Displayed; Name=2; IsoId=P78410-2; Sequence=VSP_045907; Name=3; IsoId=P78410-3; Sequence=VSP_045906
Alternative Sequence
1..42; Missing (in isoform 3); 1..28; MKMASSLAFLLLNFHVSLLLVQLLTPCS -> MGIPR (in isoform 2)
3D Structural Models
Turn
70..73; 94..96; 225..228
Helix
86..88; 91..93; 104..106; 118..120
Beta Strand
32..34; 40..43; 48..56; 63..69; 74..80; 97..100; 108..115; 122..130; 133..145; 151..158; 161..173; 176..180; 202..210; 217..224; 229..236
3D Structure
Electron microscopy (2); X-ray crystallography (1)
Domain & Motif Annotations
Coiled Coil
272..319
Domain (FT)
30..139; Ig-like V-type
Protein Families
- Immunoglobulin superfamily
- BTN/MOG family
Sequence Similarities
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Clinical Relevance
Antibody