Protein detail

BASP1

Brain acid soluble protein 1 (22 kDa neuronal tissue-enriched acidic protein) (Neuronal axonal membrane protein NAP-22)

Entry name
BASP1
UniProt ID
P80723
EVMP confidence score
0.75
Supporting publications (n)
34
Transmembrane count
Protein classification
Plasma proteinsPredicted intracellular proteinsTransporters
Basic Information
Protein Names
Brain acid soluble protein 1 (22 kDa neuronal tissue-enriched acidic protein) (Neuronal axonal membrane protein NAP-22)
Protein Class (3)
Plasma proteinsPredicted intracellular proteinsTransporters
Protein Function (2)
  • Transporters:Transporter channels and pores
  • Predicted intracellular proteins
Ensembl
ENSG00000176788
Entrez Gene Symbol
BASP1
Gene Synonym (4)
CAP-23CAP23NAP-22NAP22
Gene Description
Brain abundant membrane attached signal protein 1
Chromosome
5
Position
17065598-17276843
Supporting publications (n)
34
EVMP confidence score
0.75
Fluorescence & Localization
BASP1 fluorescence
Tissue SpecificliverCell SpecificCardiomyocytes
Function & Pathway
Protein Function (2)
  • Transporters:Transporter channels and pores
  • Predicted intracellular proteins
Cellular Component (13)
Page 1 of 2
Molecular Function (5)
Biological Process (3)
Reactome (3)
Mediation Categories
Receptor-signaling mediation
Relations & Evidence9

Ligand-Receptor Signaling (5)

5 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPI
intracellularintracellularGO_Intercell
intracellularintracellularOmniPath
plasma_membraneplasma_membraneUniProt_location
plasma_membraneplasma_membraneOmniPath

Protein Complex Composition (3)

3 records.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
HT_DM_Cluster29ABHD16AABHD16BBASP1CETN2H3-3APEX14PEX5PEX5LRPS15AWWTR1YAP1O75381O95870P41208P46937P50542P62244P80723P84243Q8IYB4Q9GZV5Q9H3Z71:1:1:1:1:1:1:2:1:1:1CompleatCompleat:HC210722036573
ATP5F1AATP5F1BATP5F1DBASP1EIF2APA2G4SERBP1P06576P25705P30049P80723Q8NC51Q9BY44Q9UQ800:0:0:0:0:0:0Havugimana2012Havugimana2012:C_536
BASP1DHX29SERBP1P80723Q7Z478Q8NC510:0:0hu.MAP2

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
UltracentrifugationFlow cytometry137862381
Sequence, Structure & Domains

Sequences

Length
227
Mass
22,693
Sequence
MGGKLSKKKKGYNVNDEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPAASAEEPKPVEAPAANSDQTVTVKE
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P80723-1; Sequence=Displayed; Name=2; IsoId=P80723-2; Sequence=VSP_037994
Alternative Sequence
88..141; Missing (in isoform 2)

Domain & Motif Annotations

Compositional Bias
1..11; Basic residues; 15..27; Basic and acidic residues; 49..105; Basic and acidic residues; 106..139; Low complexity; 140..152; Basic and acidic residues; 173..185; Polar residues; 218..227; Polar residues
Region
1..227; Disordered
Protein Families
BASP1 family
Sequence Similarities
Belongs to the BASP1 family.
Clinical Relevance
Antibody (2)
HPA045218HPA050333
Supporting Publications34
PMIDTitleRelated sentences
40189497Small extracellular vesicle-based one-step high-throughput microfluidic platform for epithelial ovarian cancer diagnosis.No related sentences available
40840701Multiomics analysis to evaluate the enrichment of extracellular vesicles from human plasma.No related sentences available
41068253Identification of plasma extracellular vesicle protein biomarkers in diabetic retinopathy progression.No related sentences available
41307968Extracellular Vesicles Define Discrete Nano-Based Niches Within the Human Haematopoietic System.No related sentences available
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