Protein detail

I5P1

Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)

Entry name
I5P1
UniProt ID
EVMP confidence score
0.38
Supporting publications (n)
Transmembrane count
Protein classification
EnzymesMetabolic proteinsPredicted intracellular proteins
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information10
Protein Names
Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)
Protein Class (3)
EnzymesMetabolic proteinsPredicted intracellular proteins
Protein Function (3)
  • Enzymes
  • Predicted intracellular proteins
  • ENZYME proteins:Hydrolases
Entrez Gene Symbol
Gene Synonym
5PTASE
Gene Description
Inositol polyphosphate-5-phosphatase A
Chromosome
10
Position
132537787-132783480
EVMP confidence score
0.38
Fluorescence & Localization3
Tissue SpecificbrainCell SpecificAstrocytesSingle-Nuclei Brain SpecificBergmann glia
Function & Pathway7
Relations & Evidence8

Ligand-Receptor Signaling (7)

7 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
receptorreceptorOmniPathNoYesNoNoNo
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo
plasma_membraneplasma_membraneUniProt_locationNoNoNoNoNo
plasma_membraneplasma_membraneOmniPathNoNoNoNoNo
receptorreceptorscConnectNoYesNoNoNo

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationMass spectrometry132396726
Sequence, Structure & Domains5

Sequences

Length
412
Mass
47,820
Sequence
MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPSVYSGIRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRKVMLQLEKKLFDYFNQEVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDARQGEQYMNTRCPAWCDRILMSPSAKELVLRSESEEKVVTYDHIGPNVCMGDHKPVFLAFRIMPGAGKPHAHVHKCCVVQ

Domain & Motif Annotations

Protein Families (3)
  • Inositol 1
  • 4
  • 5-trisphosphate 5-phosphatase type I family
Sequence Similarities
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.
Clinical Relevance1
Antibody