Protein detail
ISK13
Serine protease inhibitor Kazal-type 13 (Hepatitis B virus DNA polymerase transactivated serine protease inhibitor) (Hespintor) (Serine protease inhibitor Kazal-type 5-like 3)
Entry name ISK13 | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted intracellular proteinsPredicted secreted proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Serine protease inhibitor Kazal-type 13 (Hepatitis B virus DNA polymerase transactivated serine protease inhibitor) (Hespintor) (Serine protease inhibitor Kazal-type 5-like 3)
Protein Class (2)
Predicted intracellular proteinsPredicted secreted proteins
Protein Function (2)
- Predicted secreted proteins
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (4)
HESPINTORLiESP6MGC149260SPINK5L3
Gene Description
Serine peptidase inhibitor Kazal type 13
Chromosome
5
Position
148268180-148286255
Supporting publications (n)
1
EVMP confidence score
0.28
Fluorescence & Localization
Cell SpecificGoblet cellsBlood Cell Specificintermediate monocyteBlood Lineage Specificmonocytes
Function & Pathway
Protein Function (2)
- Predicted secreted proteins
- Predicted intracellular proteins
Cellular Component
Molecular Function (2)
Mediation Categories
Other mediation
Relations & Evidence9
Ligand-Receptor Signaling (8)
8 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| ecm | ecm | MatrixDB | Yes | Yes | |||
| ecm | ecm | OmniPath | Yes | Yes | |||
| serine_peptidase_inhibitor | secreted_peptidase_inhibitor | HGNC | Yes | ||||
| secreted_peptidase_inhibitor | secreted_peptidase_inhibitor | OmniPath | Yes | ||||
| secreted | secreted | UniProt_keyword | Yes | ||||
| secreted | secreted | UniProt_location | Yes | ||||
| secreted | secreted | HPA_secretome | Yes | ||||
| secreted | secreted | OmniPath | Yes |
Sequence, Structure & Domains
Sequences
Length
94
Mass
11,051
Sequence
MAAFPHKIIFFLVCSTLTHVAFSGIFNKRDFTRWPKPRCKMYIPLDPDYNADCPNVTAPVCASNGHTFQNECFFCVEQREFHYRIKFEKYGKCD
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q1W4C9-1; Sequence=Displayed; Name=2; IsoId=Q1W4C9-2; Sequence=VSP_034842
Alternative Sequence
1..40; Missing (in isoform 2)
Domain & Motif Annotations
Domain (FT)
33..94; Kazal-like
Clinical Relevance
Antibody
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 40784529 | Serum-derived exosome proteomics unveils the distinct and adjustable nature of the dampness constitution in traditional Chinese medicine. | No related sentences available |