Protein detail
ISK13
Serine protease inhibitor Kazal-type 13 (Hepatitis B virus DNA polymerase transactivated serine protease inhibitor) (Hespintor) (Serine protease inhibitor Kazal-type 5-like 3)
Protein symbol ISK13 | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification Predicted intracellular proteinsPredicted secreted proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Serine protease inhibitor Kazal-type 13 (Hepatitis B virus DNA polymerase transactivated serine protease inhibitor) (Hespintor) (Serine protease inhibitor Kazal-type 5-like 3)
Protein Class
Predicted intracellular proteinsPredicted secreted proteins
Protein Function
- Predicted secreted proteins
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
HESPINTORLiESP6MGC149260SPINK5L3
Gene Description
Serine peptidase inhibitor Kazal type 13
Chromosome
5
Position
148268180-148286255
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificGoblet cellsBlood Cell Specificintermediate monocyteBlood Lineage Specificmonocytes
Function & Pathway
Protein Function
- Predicted secreted proteins
- Predicted intracellular proteins
Cellular Component
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
8 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| ecm | ecm | MatrixDB | Yes | No | Yes | No | No |
| ecm | ecm | OmniPath | Yes | No | Yes | No | No |
| serine_peptidase_inhibitor | secreted_peptidase_inhibitor | HGNC | No | No | Yes | No | No |
| secreted_peptidase_inhibitor | secreted_peptidase_inhibitor | OmniPath | No | No | Yes | No | No |
| secreted | secreted | UniProt_keyword | No | No | Yes | No | No |
| secreted | secreted | UniProt_location | No | No | Yes | No | No |
| secreted | secreted | HPA_secretome | No | No | Yes | No | No |
| secreted | secreted | OmniPath | No | No | Yes | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
94
Mass
11,051
Sequence
MAAFPHKIIFFLVCSTLTHVAFSGIFNKRDFTRWPKPRCKMYIPLDPDYNADCPNVTAPVCASNGHTFQNECFFCVEQREFHYRIKFEKYGKCD
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q1W4C9-1; Sequence=Displayed; Name=2; IsoId=Q1W4C9-2; Sequence=VSP_034842
Alternative Sequence
1..40; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Domain (FT)
33..94; Kazal-like
Clinical Relevance
Antibody