Protein detail

PLPR5

Phospholipid phosphatase-related protein type 5 (Lipid phosphate phosphatase-related protein type 5) (Phosphatidic acid phosphatase type 2d) (Plasticity-related gene 5 protein) (PRG-5)

Protein symbol
PLPR5
UniProt ID
EVMP score
0.50
Frequency
2
Transmembrane count
6
Protein classification
Predicted membrane proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Phospholipid phosphatase-related protein type 5 (Lipid phosphate phosphatase-related protein type 5) (Phosphatidic acid phosphatase type 2d) (Plasticity-related gene 5 protein) (PRG-5)
Protein Class
Predicted membrane proteins
Transmembrane
10..30; Helical; 62..82; Helical; 122..142; Helical; 196..213; Helical; 225..245; Helical; 252..272; Helical
Transmembrane Count
6
Entrez Gene Symbol
Gene Synonym
LPPR5PAP2PAP2DPRG5
Gene Description
Phospholipid phosphatase related 5
Chromosome
1
Position
98890245-99227929
Frequency
2
EVMP Score
0.50
Fluorescence & Localization
Tissue SpecifictestisCell SpecificEarly primary spermatocytesSecretome LocationIntracellular and membraneSecretome FunctionNo annotated function
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

11 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
cell_surface_enzymecell_surface_enzymeSurfaceomeYesNoNoNoNo
cell_surface_enzymecell_surface_enzymeOmniPathYesNoNoNoNo
transmembranetransmembraneUniProt_locationNoNoNoNoNo
transmembranetransmembraneUniProt_topologyNoNoNoNoNo
transmembranetransmembraneUniProt_keywordNoNoNoNoNo
transmembranetransmembraneOmniPathNoNoNoNoNo
plasma_membraneplasma_membraneUniProt_locationNoNoNoNoNo
plasma_membraneplasma_membraneOmniPathNoNoNoNoNo
cell_surfacecell_surfaceSurfaceomeNoNoNoNoNo
cell_surfacecell_surfaceOmniPathNoNoNoNoNo
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Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity CaptureELISA24078452940098346
Sequence, Structure & Domains

Sequences

Length
321
Mass
35,427
Sequence
MPLLPAALTSSMLYFQMVIMAGTVMLAYYFEYTDTFTVNVQGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEKTILTGDCCYINPLVRRTVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCQQYTQFISGEEACTGNPDLIMRARKTFPSKEAALSVYAAMYLTMYITNTIKAKGTRLAKPVLCLGLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKGRQAENEHIHMDNLAQMPMISIPRVESPLEKVTSVQNHITAFAEVT
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; Synonyms=PAP2d_v1; IsoId=Q32ZL2-1; Sequence=Displayed; Name=2; Synonyms=PAP2d_v2; IsoId=Q32ZL2-2; Sequence=VSP_031828
Alternative Sequence
307..311; Missing (in isoform 2)

3D Structural Models

Domain & Motif Annotations

Protein Families
PA-phosphatase related phosphoesterase family
Sequence Similarities
Belongs to the PA-phosphatase related phosphoesterase family.
Clinical Relevance