Protein detail
ZNG1F
Zinc-regulated GTPase metalloprotein activator 1F (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 6) (COBW domain-containing protein 6)
Entry name ZNG1F | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information11
Protein Names
Zinc-regulated GTPase metalloprotein activator 1F (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 6) (COBW domain-containing protein 6)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym (2)
CBWD6CBWD7
Gene Description
Zn regulated GTPase metalloprotein activator 1F
Chromosome
9
Position
41131306-41199261
Supporting publications (n)
1
EVMP confidence score
0.38
Function & Pathway5
Protein Function
Predicted intracellular proteins
Cellular Component (2)
Molecular Function (3)
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence5
Ligand-Receptor Signaling (4)
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyImmunoaffinity Capture | Mass spectrometry | 20 | 3929045937702715327954142856233522848702268848413060870033729255221060713663540037686366381644984009834630760538313664073983538640091455380825593861251534889606 |
Sequence, Structure & Domains9
Sequences
Length
395
Mass
43,964
Sequence
MLPAVGSVDEEEDPAEEDCPELVPIETTQSEEEEKSGLGAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNESGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAIENLMQKKGKFDDILLETTGLADPGAVASMFWVDAELGSDIYLDGIITIVDSKYGLKHLTEEKPDGLINEATRQVALADIILINKTDLVPEEDVKKLRTTLRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFDVPGNAKEEHLNMFIQNLLWEKNVRNKDNHCMEVIRLKGLVSIKDKSQQVIVQGVHELCDLEETPVSWKDDTERTNRLVLIGRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT
Domain & Motif Annotations
Compositional Bias
8..20; Acidic residues
Motif
17..24; psi-PxLVp motif; 107..110; CXCC motif
Domain (FT)
274..377; CobW C-terminal
Region
1..22; Disordered
Protein Families (2)
- SIMIBI class G3E GTPase family
- ZNG1 subfamily
Sequence Similarities
Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.
Supporting Publications1
| PMID | Title | Abstract |
|---|---|---|
| 34817906 | Proteomic dissection of large extracellular vesicle surfaceome unravels interactive surface platform. | No abstract available |