Protein detail

ZNG1F

Zinc-regulated GTPase metalloprotein activator 1F (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 6) (COBW domain-containing protein 6)

Protein symbol
ZNG1F
UniProt ID
EVMP score
0.38
Frequency
1
Transmembrane count
Protein classification
Predicted intracellular proteins
Basic Information
Protein Names
Zinc-regulated GTPase metalloprotein activator 1F (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 6) (COBW domain-containing protein 6)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
CBWD6CBWD7
Gene Description
Zn regulated GTPase metalloprotein activator 1F
Chromosome
9
Position
41131306-41199261
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion ChromatographyImmunoaffinity CaptureMass spectrometry203929045937702715327954142856233522848702268848413060870033729255221060713663540037686366381644984009834630760538313664073983538640091455380825593861251534889606
Sequence, Structure & Domains

Sequences

Length
395
Mass
43,964
Sequence
MLPAVGSVDEEEDPAEEDCPELVPIETTQSEEEEKSGLGAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNESGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAIENLMQKKGKFDDILLETTGLADPGAVASMFWVDAELGSDIYLDGIITIVDSKYGLKHLTEEKPDGLINEATRQVALADIILINKTDLVPEEDVKKLRTTLRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFDVPGNAKEEHLNMFIQNLLWEKNVRNKDNHCMEVIRLKGLVSIKDKSQQVIVQGVHELCDLEETPVSWKDDTERTNRLVLIGRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT

3D Structural Models

Domain & Motif Annotations

Compositional Bias
8..20; Acidic residues
Motif
17..24; psi-PxLVp motif; 107..110; CXCC motif
Domain (FT)
274..377; CobW C-terminal
Region
1..22; Disordered
Protein Families
  • SIMIBI class G3E GTPase family
  • ZNG1 subfamily
Sequence Similarities
Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.
Clinical Relevance