Protein detail
ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 3) (COBW domain-containing protein 3)
Protein symbol ZNG1C | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
Basic Information
Protein Names
Zinc-regulated GTPase metalloprotein activator 1C (EC 3.6.5.-) (Cobalamin synthase W domain-containing protein 3) (COBW domain-containing protein 3)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
bA561O23.1CBWD3
Gene Description
Zn regulated GTPase metalloprotein activator 1C
Chromosome
9
Position
68232003-68300035
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificEarly spermatidsSingle-Nuclei Brain Specificendothelial cellBlood Lineage Specificdendritic cells
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Western BlottingMass Spectrometry | 1 | 36573687 |
Sequence, Structure & Domains
Sequences
Length
395
Mass
44,038
Sequence
MLPAVGSVDEEEDPAEEDCPELVPIETTQSEEEEKSGLGAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNESGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAIENLMQKKGKFDDILLETTGLADPGAVASMFWVDAELGSDIYLDGIITIVDSKYGLKHLTEEKPDGLINEATRQVALADIILINKTDLVPEEDVKKLRTTIRSINGLGQILETQRSRVDLSNVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFEVPGNAKEEHLNMFIQNLLWEKNVRNKDNHCMEVIRLKGLVSIKDKSQQVIVQGVHELYDLEETPVSWKDDTERTNRLVLIGRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q5JTY5-1; Sequence=Displayed; Name=2; IsoId=Q5JTY5-2; Sequence=VSP_055975
Alternative Sequence
145..164; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
8..20; Acidic residues
Motif
17..24; psi-PxLVp motif; 107..110; CXCC motif
Domain (FT)
274..377; CobW C-terminal
Region
1..22; Disordered
Protein Families
- SIMIBI class G3E GTPase family
- ZNG1 subfamily
Sequence Similarities
Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.