Protein detail
CF157
Cilia- and flagella-associated protein 157
Entry name CF157 | UniProt ID | EVMP confidence score 0.38 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40Basic Information11
Protein Names
Cilia- and flagella-associated protein 157
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
C9orf117
Gene Description
Cilia and flagella associated protein 157
Chromosome
9
Position
127706988-127716002
Supporting publications (n)
1
EVMP confidence score
0.38
Fluorescence & Localization3
Cell SpecificEnterocytesSingle-Nuclei Brain Specificendothelial cellBlood Cell Specificplasmacytoid DC
Function & Pathway5
Protein Function
Predicted intracellular proteins
Cellular Component (4)
Molecular Function
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence5
Ligand-Receptor Signaling (4)
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationSize Exclusion Chromatography | Western blotting|Mass spectrometry|FACSMass spectrometryR Sequencing | 1 | 36573687 |
Sequence, Structure & Domains10
Sequences
Length
520
Mass
60,533
Sequence
MAPKKSVSKAGKELEVKKKGGKKEPVVAVEPPLAKEMKEFYHIQIRDLEDRLARYQRKWDELAVQEKMFRQEFEQLANNKKEIVAFLKRTLNQQVDEITDLNEQLQNLQLAKEMEKDAFEAQLAQVRHEFQETKDQLTTENIILGGKLAALEEFRLQKEEVTDKFTLLEEQVRKQENEFRDYAYNLEKKSVLDKDRLRKEIIQRVNLVANEFHKVTTNRMWETTKRAIKENNGITLQMARVSQQGMKLLQENEQLKGRQNNLCKQLELLENTQKVMARHKRGHQKIILMLTKKCQEQQQDTKEAEELRLLLSQLEQRSLQLQVDNQALKSQRDQLSLQLEQQQVDLQRLQQELANEQKVRASLEAALVQATSFLQNILQMHRDEEDSDVDVTFQPWHKEMLQQLLVMLSSTVATRPQKAACPHQESQSHGPPKESRPSIQLPRTGSLLPQLSDITPYQPGDLGLVPRQVHIPPNPQDLRLLSYITRVGTFRAHSSPEMRAPGSLKRLEKFSLPEVPLRPK
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q5JU67-1; Sequence=Displayed; Name=2; IsoId=Q5JU67-2; Sequence=VSP_028641, VSP_028642
Alternative Sequence
380..425; MHRDEEDSDVDVTFQPWHKEMLQQLLVMLSSTVATRPQKAACPHQE -> TGKTSWKWALRLEFPGRGWVLGPLWACCHPTLTNRCTAMKRTVTLT (in isoform 2); 426..520; Missing (in isoform 2)
Domain & Motif Annotations
Compositional Bias
10..22; Basic and acidic residues; 437..453; Polar residues
Coiled Coil
33..189; 236..372
Region
1..22; Disordered; 416..453; Disordered
Protein Families
CFAP157 family
Sequence Similarities
Belongs to the CFAP157 family.
Supporting Publications1
| PMID | Title | Abstract |
|---|---|---|
| 36982312 | Saliva and Saliva Extracellular Vesicles for Biomarker Candidate Identification-Assay Development and Pilot Study in Amyotrophic Lateral Sclerosis. | No abstract available |