Protein detail

F209A

Protein FAM209A

Entry name F209A	UniProt ID Q5JX71	EVMP confidence score 0.50
Supporting publications (n) 3	Transmembrane count 1	Protein classification

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information7

Protein Names

Protein FAM209A

Transmembrane

53..73; Helical

Transmembrane Count

Ensembl

ENSG00000124103

Entrez Gene Symbol

FAM209A

Supporting publications (n)

EVMP confidence score

0.50

Fluorescence & Localization3

Cell SpecificAlveolar cells type 1Blood Cell SpecificneutrophilBlood Lineage Specificgranulocytes

Function & Pathway4

Cellular Component (3)

Molecular Function (2)

Biological Process (3)

Mediation Categories

Other mediation

Relations & Evidence15

Ligand-Receptor Signaling (12)

12 records.

Category	Parent	Database	Transmitter	Receiver	Secreted	Plasma Membrane (Transmembrane)	Plasma Membrane (Peripheral)
transmembrane_phobius	transmembrane_predicted	Almen2009	No	No	No	No	No
transmembrane_sosui	transmembrane_predicted	Almen2009	No	No	No	No	No

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Protein Complex Composition (2)

2 records.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
	FAM209A UBASH3B	Q5JX71 Q8TF42	0:0	hu.MAPhu.MAP2
	FAM209A RCHY1 UBASH3B	Q5JX71 Q8TF42 Q96PM5	0:0:0	hu.MAP2

Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion Chromatography	Mass spectrometry	4	32795414 33035814 39940641 39940641

Sequence, Structure & Domains7

Sequences

Length

171

Mass

19,603

Sequence

MWTLKSSLVLLLCLTCSYAFMFSSLRQKTSEPQGKVQYGEHFRIRQNLPEHTQGWLGSKWLWLLFVVVPFVILQCQRDSEKNKEQSPPGLRGGQLHSPLKKKRNASPNKDCAFNTLMELEVELMKFVSKVRNLKRAMATGSGSNLRLRKSEMPADPYHVTICEIWGEESSS

Domain & Motif Annotations

Coiled Coil

114..139

Region

81..107; Disordered

Protein Families

FAM209 family

Sequence Similarities

Belongs to the FAM209 family.

Supporting Publications3

PMID	Title	Abstract
26775013	Proteomic characterization of circulating extracellular vesicles identifies novel serum myeloma associated markers.	No abstract available
38136601	Identification of Central Nervous System Oncologic Disease Biomarkers in EVs from Cerebrospinal Fluid (CSF) of Pediatric Patients: A Pilot Neuro-Proteomic Study.	No abstract available
40098346	Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays.	No abstract available