Protein detail

BEND6

BEN domain-containing protein 6

Protein symbol
BEND6
UniProt ID
EVMP score
0.38
Frequency
1
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
BEN domain-containing protein 6
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
bA203B9.1C6orf65FLJ30162
Gene Description
BEN domain containing 6
Chromosome
6
Position
56955107-57027346
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificLate primary spermatocytesSecretome LocationSecreted to bloodSecretome FunctionOther
Function & Pathway
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

3 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

1 record.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
BEND6Q5SZJ82PDBPDB:7yun

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyFlow cytometryMORPHELISA24078452941216884
Sequence, Structure & Domains

Sequences

Length
279
Mass
31,222
Sequence
MQKIVQTDEITNTQAFRKGKRKRTETMDSENANSDMDKGQRDPYSGNAFLPGESSSEDEEPLAELSKEELCAKIKSLKEKLTNTRKENSRLRQSLVMLQVLPQAVTQFEELVGMAEALLKGGGTMSTSASTLWRATNNSSPDSFASTCSNSNSNSSSPVSLKPEEEHQTDEKQFQIEKWQIARCNKSKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKAVKPAMNQNEVQEIIGVTKQLFPNTDDVSIRRMIGQKLNNCTKKPNLSKNLNSQDIK
Alternative Products
Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q5SZJ8-1; Sequence=Displayed; Name=2; IsoId=Q5SZJ8-2; Sequence=VSP_026963, VSP_026964; Name=3; IsoId=Q5SZJ8-3; Sequence=VSP_026961, VSP_026962; Name=4; IsoId=Q5SZJ8-4; Sequence=VSP_026965, VSP_026966
Alternative Sequence
1..98; Missing (in isoform 3); 99..100; QV -> ML (in isoform 3); 100..106; VLPQAVT -> AWSRELP (in isoform 2); 107..279; Missing (in isoform 2); 181..189; IARCNKSKP -> NPLLQGTKL (in isoform 4); 190..279; Missing (in isoform 4)

3D Structural Models

Helix
178..182; 189..200; 203..207; 230..243; 249..262
Beta Strand
210..212
3D Structure
X-ray crystallography (2)

Domain & Motif Annotations

Compositional Bias
1..15; Polar residues; 134..148; Polar residues; 162..172; Basic and acidic residues
Coiled Coil
62..99
Domain (FT)
171..271; BEN
Region
1..65; Disordered; 134..172; Disordered
Clinical Relevance