Protein detail
HENMT
Small RNA 2'-O-methyltransferase (EC 2.1.1.386) (HEN1 methyltransferase homolog 1)
Protein symbol HENMT | UniProt ID | EVMP score 0.38 |
Frequency 1 | Transmembrane count | Protein classification EnzymesPredicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Small RNA 2'-O-methyltransferase (EC 2.1.1.386) (HEN1 methyltransferase homolog 1)
Protein Class
EnzymesPredicted intracellular proteins
Protein Function
- ENZYME proteins:Transferases
- Enzymes
- Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
C1orf59FLJ30525HEN1
Gene Description
HEN methyltransferase 1
Chromosome
1
Position
108648290-108661526
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificMyonuclei
Function & Pathway
Protein Function
- ENZYME proteins:Transferases
- Enzymes
- Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Differential UltracentrifugationUltrafiltration / Tangential Flow FiltrationSize Exclusion Chromatography | Mass spectrometry | 20 | 3929045939949490315085003822545339873726327954143873186827723984337095102731242837686366384909583910427941201090341862433076053831320591403116163983538640091455 |
Sequence, Structure & Domains
Sequences
Length
393
Mass
44,525
Sequence
MEENNLQCSSVVDGNFEEVPRETAIQFKPPLYRQRYQFVKNLVDQHEPKKVADLGCGDTSLLRLLKVNPCIELLVGVDINEDKLRWRGDSLAPFLGDFLKPRDLNLTITLYHGSVVERDSRLLGFDLITCIELIEHLDSGDLARFPEVVFGYLSPSMIVISTPNSEFNPLFPSVTLRDSDHKFEWTRMEFQTWALYVANRYDYSVEFTGVGEPPAGAENVGYCTQIGIFRKNGGKATESCLSEQHDQHVYKAVFTTSYPSLQQERFFKLVLVNEVSQQVESLRVSHLPRRKEQAGERGDKPKDIGGSKAPVPCFGPVFTEVEKAKIENSPTPFCVGDKFFVPLQRLLAYPKLNRLCANEEMMRSVIADSIPLSSDGSAVVADLRNYFDEQFEF
3D Structural Models
Turn
150..153
Helix
31..46; 60..65; 81..84; 89..91; 95..99; 120..122; 134..136; 139..149; 165..167; 178..180; 187..201; 218..220
Beta Strand
49..54; 72..79; 102..104; 106..112; 126..132; 156..164; 203..210; 223..231; 250..258
3D Structure
X-ray crystallography (2)
Domain & Motif Annotations
Compositional Bias
290..305; Basic and acidic residues
Region
286..307; Disordered
Protein Families
- Methyltransferase superfamily
- HEN1 family
Sequence Similarities
Belongs to the methyltransferase superfamily. HEN1 family.