Protein detail

PXDC1

PX domain-containing protein 1

Entry name
PXDC1
UniProt ID
EVMP confidence score
0.38
Supporting publications (n)
1
Transmembrane count
Protein classification
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information6
Protein Names
PX domain-containing protein 1
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Supporting publications (n)
1
EVMP confidence score
0.38
Fluorescence & Localization7
PXDC1 fluorescence
Cell SpecificcDCSingle-Nuclei Brain Specificendothelial cellBlood Cell Specificmyeloid DCBlood Lineage Specificdendritic cellsSecretome LocationSecreted to bloodSecretome FunctionNo annotated function
Function & Pathway4
Protein Function
Predicted intracellular proteins
Mediation Categories
Other mediation
Relations & Evidence7

Ligand-Receptor Signaling (2)

2 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Protein Complex Composition (4)

4 records.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
PXDC1RABGAP1LB7ZAP0Q5TGL80:0hu.MAP2
PXDC1RABGAP1RABGAP1LB7ZAP0Q5TGL8Q9Y3P90:0:0hu.MAP
PXDC1RABGAP1LQ5R372Q5TGL80:0hu.MAP2
PXDC1RABGAP1RABGAP1LQ5R372Q5TGL8Q9Y3P90:0:0hu.MAP

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity CaptureWestern blotting23929045940098346
Sequence, Structure & Domains4

Sequences

Length
231
Mass
26,560
Sequence
MASAVFEGTSLVNMFVRGCWVNGIRRLIVSRRGDEEEFFEIRTEWSDRSVLYLHRSLADLGRLWQRLRDAFPEDRSELAQGPLRQGLVAIKEAHDIETRLNEVEKLLKTIISMPCKYSRSEVVLTFFERSPLDQVLKNDNVHKIQPSFQSPVKISEIMRSNGFCLANTETIVIDHSIPNGRDQQLGVDPTEHLFENGSEFPSELEDGDDPAAYVTNLSYYHLVPFETDIWD

Domain & Motif Annotations

Domain (FT)
1..134; PX
Supporting Publications1
PMIDTitleAbstract
32560723T2 and T17 cytokines alter the cargo and function of airway epithelium-derived extracellular vesicles.No abstract available