Protein detail

PXDC1

PX domain-containing protein 1

Protein symbol
PXDC1
UniProt ID
EVMP score
0.38
Frequency
1
Transmembrane count
Protein classification
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
PX domain-containing protein 1
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificcDCSingle-Nuclei Brain Specificendothelial cellBlood Cell Specificmyeloid DCBlood Lineage Specificdendritic cellsSecretome LocationSecreted to bloodSecretome FunctionNo annotated function
Function & Pathway
Protein Function
Predicted intracellular proteins
Mediation Categories
Other mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

2 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

4 records.

Component NameComponent Gene SymbolsComponent UniProt IDStoichiometryDatabaseDatabase IDsReferences
PXDC1RABGAP1LB7ZAP0Q5TGL80:0hu.MAP2
PXDC1RABGAP1RABGAP1LB7ZAP0Q5TGL8Q9Y3P90:0:0hu.MAP
PXDC1RABGAP1LQ5R372Q5TGL80:0hu.MAP2
PXDC1RABGAP1RABGAP1LQ5R372Q5TGL8Q9Y3P90:0:0hu.MAP

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyImmunoaffinity CaptureWestern blotting23929045940098346
Sequence, Structure & Domains

Sequences

Length
231
Mass
26,560
Sequence
MASAVFEGTSLVNMFVRGCWVNGIRRLIVSRRGDEEEFFEIRTEWSDRSVLYLHRSLADLGRLWQRLRDAFPEDRSELAQGPLRQGLVAIKEAHDIETRLNEVEKLLKTIISMPCKYSRSEVVLTFFERSPLDQVLKNDNVHKIQPSFQSPVKISEIMRSNGFCLANTETIVIDHSIPNGRDQQLGVDPTEHLFENGSEFPSELEDGDDPAAYVTNLSYYHLVPFETDIWD

3D Structural Models

Domain & Motif Annotations

Domain (FT)
1..134; PX
Clinical Relevance