Protein detail
FLTOP
Protein Flattop (Cilia- and flagella-associated protein 126)
Protein symbol FLTOP | UniProt ID | EVMP score 0.50 |
Frequency 2 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Protein Flattop (Cilia- and flagella-associated protein 126)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
C1orf192FlattopFltp
Gene Description
Cilia and flagella associated protein 126
Chromosome
1
Position
161364733-161367876
Frequency
2
EVMP Score
0.50
Fluorescence & Localization
Tissue SpecifickidneyCell SpecificProximal tubule cells
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Biological Process
Mediation Categories
Fusion and delivery mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
6 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
| plasma_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| apical_cell_membrane | plasma_membrane | UniProt_location | No | No | No | No | No |
| plasma_membrane | plasma_membrane | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
177
Mass
19,293
Sequence
MATNYSANQYEKAFSSKYLQNWSPTKPTKESISSHEGYTQIIANDRGHLLPSVPRSKANPWGSFMGTWQMPLKIPPARVTLTSRTTAGAASLTKWIQKNPDLLKASNGLCPEILGKPHDPDSQKKLRKKSITKTVQQARSPTIIPSSPAANLNSPDELQSSHPSAGHTPGPQRPAKS
3D Structural Models
3D Structure
Electron microscopy (2)
Domain & Motif Annotations
Compositional Bias
115..124; Basic and acidic residues; 132..163; Polar residues
Region
113..177; Disordered
Protein Families
Flattop family
Sequence Similarities
Belongs to the Flattop family.
Clinical Relevance
Antibody