Protein detail
LRCH2
Leucine-rich repeat and calponin homology domain-containing protein 2
Entry name LRCH2 | UniProt ID | EVMP score 0.38 |
Frequency 4 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Leucine-rich repeat and calponin homology domain-containing protein 2
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
KIAA1495
Gene Description
Leucine rich repeats and calponin homology domain containing 2
Chromosome
X
Position
115110616-115234096
Frequency
4
EVMP Score
0.38
Fluorescence & Localization
Cell SpecificLymphatic endothelial cellsSingle-Nuclei Brain Specificendothelial cell
Function & Pathway
Protein Function
Predicted intracellular proteins
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
2 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Mass spectrometry | 0 |
Sequence, Structure & Domains
Sequences
Length
765
Mass
84,588
Sequence
MAASQGGGGNSGGGGCGGGGSSGGCGTAGGGGGGAGGGGGGGGGTLVVPIPVPTLFGQPFPNGPPWNPGSLQPQHTVRSLDRALEEAGSSGILSLSGRKLRDFPGSGYDLTDTTQADLSRNRFTEIPSDVWLFAPLETLNLYHNCIKTIPEAIKNLQMLTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSLRELNIRRNNLHVLPDELGDLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLKGKVHIFKYLNIQACCRMDKKPDSLDLPSLSKRMPSQPLTDSMEDFYPNKNHGPDSGIGSDNGEKRLSTTEPSDDDTVSLHSQVSESNREQTSRNDSHIIGSKTDSQKDQEVYDFVDPNTEDVAVPEQGNAHIGSFVSFFKGKEKCSEKSRKNEELGDEKRLEKEQLLAEEEDDDLKEVTDLRKIAAQLLQQEQKNRILNHSTSVMRNKPKQTVECEKSVSADEVNSPLSPLTWQPLENQKDQIDEQPWPESHPIIWQSEERRRSKQIRKEYFKYKSMRKSSSGNENDEQDSDNANMSTQSPVSSEEYDRTDGFSHSPFGLKPRSAFSRSSRQEYGAADPGFTMRRKMEHLREEREQIRQLRNNLESRLKVILPDDIGAALMDGVVLCHLANHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLDACKKLGVSQERLCLPHHILEERGLVKVGVTVQALLELPTTKASQLSVA
Alternative Products
Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q5VUJ6-1; Sequence=Displayed; Name=2; IsoId=Q5VUJ6-2; Sequence=VSP_044969
Alternative Sequence
580..596; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
378..388; Basic and acidic residues; 503..512; Basic and acidic residues; 518..529; Polar residues; 584..595; Polar residues
Repeat
89..110; LRR 1; 112..133; LRR 2; 135..156; LRR 3; 158..179; LRR 4; 180..201; LRR 5; 203..224; LRR 6; 226..248; LRR 7; 249..269; LRR 8; 271..292; LRR 9
Coiled Coil
438..472
Domain (FT)
642..755; Calponin-homology (CH)
Region
1..39; Disordered; 55..76; Disordered; 316..401; Disordered; 498..552; Disordered; 565..628; Disordered