Protein detail
TM268
Transmembrane protein 268
Entry name TM268 | UniProt ID | EVMP confidence score 0.28 |
Supporting publications (n) 3 | Transmembrane count 2 | Protein classification Predicted membrane proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Transmembrane protein 268
Protein Class
Predicted membrane proteins
Transmembrane
105..125; Helical; 132..152; Helical
Transmembrane Count
2
Ensembl
Entrez Gene Symbol
Gene Synonym (3)
C9orf91DKFZp547P234FLJ38045
Gene Description
Transmembrane protein 268
Chromosome
9
Position
114611206-114646422
Supporting publications (n)
3
EVMP confidence score
0.28
Fluorescence & Localization
Cell SpecificNeutrophilsSingle-Nuclei Brain Specificcentral nervous system macrophage
Function & Pathway
Cellular Component (2)
Molecular Function (2)
Biological Process (3)
Mediation Categories
Other mediation
Relations & Evidence11
Ligand-Receptor Signaling (10)
10 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | OmniPath | |||||
| transmembrane | transmembrane | UniProt_location | |||||
| transmembrane | transmembrane | UniProt_topology | |||||
| transmembrane | transmembrane | UniProt_keyword | |||||
| transmembrane | transmembrane | Ramilowski_location | |||||
| transmembrane | transmembrane | OmniPath | |||||
| plasma_membrane | plasma_membrane | UniProt_location | |||||
| plasma_membrane | plasma_membrane | OmniPath | |||||
| transmembrane | transmembrane_predicted | Phobius |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Mass spectrometry | 0 |
Sequence, Structure & Domains
Sequences
Length
342
Mass
37,569
Sequence
MACEPQVDPGATGPLPPSSPGWSALPGGSPPGWGQELHNGQVLTVLRIDNTCAPISFDLGAAEEQLQTWGIQVPADQYRSLAESALLEPQVRRYIIYNSRPMRLAFAVVFYVVVWANIYSTSQMFALGNHWAGMLLVTLAAVSLTLTLVLVFERHQKKANTNTDLRLAAANGALLRHRVLLGVTDTVEGCQSVIQLWFVYFDLENCVQFLSDHVQEMKTSQESLLRSRLSQLCVVMETGVSPATAEGPENLEDAPLLPGNSCPNERPLMQTELHQLVPEAEPEEMARQLLAVFGGYYIRLLVTSQLPQAMGTRHTNSPRIPCPCQLIEAYILGTGCCPFLAR
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q5VZI3-1; Sequence=Displayed; Name=2; IsoId=Q5VZI3-2; Sequence=VSP_023426; Name=3; IsoId=Q5VZI3-3; Sequence=VSP_023427
Alternative Sequence
1..35; MACEPQVDPGATGPLPPSSPGWSALPGGSPPGWGQ -> MVITQPDEASGLLP (in isoform 2); 71; I -> IQ (in isoform 3)
Domain & Motif Annotations
Region
1..30; Disordered
Clinical Relevance
Antibody
Supporting Publications3
| PMID | Title | Related sentences |
|---|---|---|
| 37686366 | Identification of a Non-Invasive Urinary Exosomal Biomarker for Diabetic Nephropathy Using Data-Independent Acquisition Proteomics. | No related sentences available |
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No related sentences available |
| 39443544 | Profiling of urinary extracellular vesicle protein signatures from patients with cribriform and intraductal prostate carcinoma in a cross-sectional study. | No related sentences available |