Protein detail

LIPJ

Lipase member J (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 1)

Entry name LIPJ	UniProt ID Q5W064	EVMP confidence score 0.38
Supporting publications (n) 1	Transmembrane count	Protein classification Predicted intracellular proteins

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40

Basic Information11

Protein Names

Lipase member J (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 1)

Protein Class

Predicted intracellular proteins

Protein Function

Predicted intracellular proteins

Ensembl

ENSG00000204022

Entrez Gene Symbol

LIPJ

Gene Synonym (2)

bA425M17.2LIPL1

Gene Description

Lipase family member J

Chromosome

Position

88586753-88606976

Supporting publications (n)

EVMP confidence score

0.38

Fluorescence & Localization3

Tissue SpecificbrainCell SpecificPituicytes/FSCs

Function & Pathway6

Protein Function

Predicted intracellular proteins

Cellular Component

GO:0043231 intracellular membrane-bounded organelle

Molecular Function (2)

GO:0016788 hydrolase activity
acting on ester bonds

Biological Process (3)

Reactome (2)

Mediation Categories

Other mediation

Relations & Evidence2

Protein Complex Composition (1)

1 record.

Component Name	Component Gene Symbols	Component UniProt ID	Stoichiometry	Database	Database IDs	References
	ATXN2 LIPJ	Q5W064 Q99700	0:0	hu.MAP

Isolation & Detection Technology (1)

1 record.

EV Isolation Method	Detection Method	Number of References	References
Differential UltracentrifugationSize Exclusion Chromatography	R Sequencing	5	40928027 33709510 37922300 39835386 40091455

Sequence, Structure & Domains5

Sequences

Length

366

Mass

42,388

Sequence

MNISQIISYWGYPDEEYDIVTEDGYILGLYRIPYWRTDNNKNLAQRVVVYLQHGLLTSASSWISNLPNNSLGFILADAGYDVWMGNSRGNTWSRKHLYLETSSKEFWAFSFDEMAKYDLPASIDFTVKQTRQEEIFYVGHSQGTTIGFITFSTISKIAERIKIFFALAPVFSTKYLKSPLIRMTYKWKSIVMAFSGNKDFLPKTSFKKFIGSKLCPLQIFDKICLNILFMMFGYDPKNLNMSRLDVYFSHNPAGTSVQNMLHWSQLLNSTHLKAYDWGSPDLNLVHYNQTTSPLYNMTNMNVATAIWNGKSDLLADPEDVNILHSEITNHIYYKTISYYNHIDSLFGLDVYDQVYHEIIDIIQDNL

Domain & Motif Annotations

Protein Families (2)

AB hydrolase superfamily
Lipase family

Sequence Similarities

Belongs to the AB hydrolase superfamily. Lipase family.

Clinical Relevance1

Antibody

HPA048594

Supporting Publications1

PMID	Title	Abstract
38347590	Revealing role of epigenetic modifiers and DNA oxidation in cell-autonomous regulation of Cancer stem cells.	The exosomes cargo includes histone 3, lysine 4 (H3K4) methyltransferases - KMT2B and KMT2D.