Protein detail
LEMD1
LEM domain-containing protein 1 (Cancer/testis antigen 50) (CT50) (LEM domain protein 1) (LEMP-1)
Entry name LEMD1 | UniProt ID | EVMP score 0.50 |
Frequency 1 | Transmembrane count 1 | Protein classification |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
LEM domain-containing protein 1 (Cancer/testis antigen 50) (CT50) (LEM domain protein 1) (LEMP-1)
Protein Function
Predicted intracellular proteins
Transmembrane
152..172; Helical; Signal-anchor for type II membrane protein
Transmembrane Count
1
Ensembl
Entrez Gene Symbol
Frequency
1
EVMP Score
0.50
Fluorescence & Localization
Tissue Specificheart muscleCell SpecificCardiomyocytes
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
12 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| transmembrane_sosui | transmembrane_predicted | Almen2009 | No | No | No | No | No |
| transmembrane_tmhmm | transmembrane_predicted | Almen2009 | No | No | No | No | No |
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Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Sequence, Structure & Domains
Sequences
Length
181
Mass
20,326
Sequence
MVDVKCLSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDSDDSEELNIILQGNIILSTEKSKKLKKWPEASTTKRKAVDTYCLDYKPSKGRRWAARAPSTRITYGTITKERDYCAEDQTIESWREEGFPVGLKLAVLGIFIIVVFVYLTVENKSLFG
Alternative Products
Event=Alternative splicing; Named isoforms=6; Name=1; Synonyms=LEMD1A; IsoId=Q68G75-1; Sequence=Displayed; Name=2; Synonyms=LEMD1B; IsoId=Q68G75-2; Sequence=VSP_024848, VSP_024849; Name=3; Synonyms=LEMD1C; IsoId=Q68G75-3; Sequence=VSP_024846; Name=4; Synonyms=LEMD1D; IsoId=Q68G75-4; Sequence=VSP_024852, VSP_024853; Name=5; Synonyms=LEMD1E; IsoId=Q68G75-5; Sequence=VSP_024851, VSP_024854; Name=6; Synonyms=LEMD1F; IsoId=Q68G75-6; Sequence=VSP_024847, VSP_024850
Alternative Sequence
28..69; PSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDSDDSEE -> Q (in isoform 3); 28..67; PSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDSDDS -> RGLQEHQAPESHMGLSPKRETTARKTRLSRAGEKKVSQWA (in isoform 6); 28..29; PS -> LA (in isoform 2); 30..181; Missing (in isoform 2); 68..181; Missing (in isoform 6); 69..108; ELNIILQGNIILSTEKSKKLKKWPEASTTKRKAVDTYCLD -> GGLQEHQAPESHMGLSPKRETTARKTRLSRAGEKKVSQWA (in isoform 5); 69..70; EL -> VA (in isoform 4); 71..181; Missing (in isoform 4); 109..181; Missing (in isoform 5)
3D Structural Models
Domain & Motif Annotations
Domain (FT)
1..45; LEM