Protein detail
R7BP
Regulator of G-protein signaling 7-binding protein (R7 family-binding protein)
Entry name R7BP | UniProt ID | EVMP confidence score 0.40 |
Supporting publications (n) 1 | Transmembrane count | Protein classification Predicted intracellular proteins |
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.70High >= 0.60Medium >= 0.40Low >= 0.30Basic Information
Protein Names
Regulator of G-protein signaling 7-binding protein (R7 family-binding protein)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
R7BP
Gene Description
Regulator of G protein signaling 7 binding protein
Chromosome
5
Position
64506015-64612319
Supporting publications (n)
1
EVMP confidence score
0.40
Fluorescence & Localization
Tissue SpecificintestineCell SpecificB-cellsBlood Cell Specificmemory B-cellBlood Lineage SpecificB-cells
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component (11)
- GO:0005634 nucleus
- GO:0005737 cytoplasm
- GO:0030424 axon
- GO:0042734 presynaptic membrane
- GO:0043005 neuron projection
- GO:0043198 dendritic shaft
- GO:0043204 perikaryon
- GO:0044327 dendritic spine head
- GO:0098794 postsynapse
- GO:0098839 postsynaptic density membrane
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Mediation Categories
Other mediation
Relations & Evidence9
Ligand-Receptor Signaling (8)
8 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| gpcr | receptor | DGIdb | Yes | ||||
| receptor | receptor | OmniPath | Yes | ||||
| intracellular | intracellular | ComPPI | |||||
| intracellular | intracellular | GO_Intercell | |||||
| intracellular | intracellular | UniProt_location | |||||
| intracellular | intracellular | OmniPath | |||||
| plasma_membrane | plasma_membrane | UniProt_location | |||||
| plasma_membrane | plasma_membrane | OmniPath |
Isolation & Detection Technology (1)
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Immunofluorescence | Western BlottingMass Spectrometry | 1 | 36736734 |
Sequence, Structure & Domains
Sequences
Length
257
Mass
28,962
Sequence
MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLISS
Domain & Motif Annotations
Compositional Bias
32..45; Basic and acidic residues; 180..192; Low complexity
Motif
242..247; Nuclear localization signal
Domain (CC)
The nuclear localization signal is both required for nuclear localization and palmitoylation.
Region
1..45; Disordered; 174..196; Disordered
Protein Families
RGS7BP/RGS9BP family
Sequence Similarities
Belongs to the RGS7BP/RGS9BP family.
Clinical Relevance
Antibody
Supporting Publications1
| PMID | Title | Related sentences |
|---|---|---|
| 38731868 | The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. | No related sentences available |