Protein detail

FA53A

Protein FAM53A (Dorsal neural-tube nuclear protein)

Entry name
FA53A
UniProt ID
EVMP confidence score
0.38
Supporting publications (n)
1
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information11
Protein Names
Protein FAM53A (Dorsal neural-tube nuclear protein)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
DNTNP
Gene Description
Family with sequence similarity 53 member A
Chromosome
4
Position
1617915-1684313
Supporting publications (n)
1
EVMP confidence score
0.38
Fluorescence & Localization2
Tissue SpecificliverCell SpecificBreast lactating cells
Function & Pathway4
Protein Function
Predicted intracellular proteins
Cellular Component
Mediation Categories
Other mediation
Relations & Evidence5

Ligand-Receptor Signaling (4)

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyWestern blotting3409280273873186833709510
Sequence, Structure & Domains8

Sequences

Length
398
Mass
42,585
Sequence
MVTLITEKLQSQSLDDLTCKAEAGPLQYSAETLNKSGRLFPLELNDQSPWKVFSGGPPVRSQAATGPDFSFLPGLSAAAHTMGLQWQPQSPRPGAGLGAASTVDPSESTGSSTAPPTKRHCRSLSEPEELVRCRSPWRPGSSKVWTPVSKRRCDSGGSATRQGSPGAVLPRSAVWSTGPTSPATPRPSSASGGFVDSSEGSAGSGPLWCSAESCLPSTRRRPSLSQERLAGAGTPLPWASSSPTSTPALGGRRGLLRCRSQPCVLSGKRSRRKRRREEDARWTRPSLDFLKMTQTLKNSKSLCSLNYEDDDEDDTPVKTVLSSPCDSRGLPGITMPGCSQRGLRTSPVHPNLWASRESVTSDGSRRSSGDPRDGDSVGEEGVFPRARWELDLEQIENN

Domain & Motif Annotations

Compositional Bias
103..115; Polar residues; 123..132; Basic and acidic residues; 176..193; Low complexity; 234..250; Low complexity; 363..375; Basic and acidic residues
Motif
268..276; Nuclear localization signal
Region
85..253; Disordered; 336..398; Disordered
Protein Families
FAM53 family
Sequence Similarities
Belongs to the FAM53 family.
Clinical Relevance1
Supporting Publications1
PMIDTitleAbstract
38037300Proteomic profiling of paired human liver homogenate and tissue derived extracellular vesicles.No abstract available