Protein detail

FA53A

Protein FAM53A (Dorsal neural-tube nuclear protein)

Protein symbol
FA53A
UniProt ID
EVMP score
0.38
Frequency
1
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
Protein FAM53A (Dorsal neural-tube nuclear protein)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym
DNTNP
Gene Description
Family with sequence similarity 53 member A
Chromosome
4
Position
1617915-1684313
Frequency
1
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificliverCell SpecificBreast lactating cells
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Mediation Categories
Other mediation
Relations & Evidence

Enzyme-Mediated Modification

0 records.

Ligand-Receptor Signaling

4 records.

CategoryParentDatabaseTransmitterReceiverSecretedPlasma Membrane (Transmembrane)Plasma Membrane (Peripheral)
intracellularintracellularComPPINoNoNoNoNo
intracellularintracellularGO_IntercellNoNoNoNoNo
intracellularintracellularUniProt_locationNoNoNoNoNo
intracellularintracellularOmniPathNoNoNoNoNo

Regulatory Interaction Network

0 records.

Protein Complex Composition

0 records.

Isolation & Detection Technology

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationSize Exclusion ChromatographyWestern blotting3409280273873186833709510
Sequence, Structure & Domains

Sequences

Length
398
Mass
42,585
Sequence
MVTLITEKLQSQSLDDLTCKAEAGPLQYSAETLNKSGRLFPLELNDQSPWKVFSGGPPVRSQAATGPDFSFLPGLSAAAHTMGLQWQPQSPRPGAGLGAASTVDPSESTGSSTAPPTKRHCRSLSEPEELVRCRSPWRPGSSKVWTPVSKRRCDSGGSATRQGSPGAVLPRSAVWSTGPTSPATPRPSSASGGFVDSSEGSAGSGPLWCSAESCLPSTRRRPSLSQERLAGAGTPLPWASSSPTSTPALGGRRGLLRCRSQPCVLSGKRSRRKRRREEDARWTRPSLDFLKMTQTLKNSKSLCSLNYEDDDEDDTPVKTVLSSPCDSRGLPGITMPGCSQRGLRTSPVHPNLWASRESVTSDGSRRSSGDPRDGDSVGEEGVFPRARWELDLEQIENN

3D Structural Models

Domain & Motif Annotations

Compositional Bias
103..115; Polar residues; 123..132; Basic and acidic residues; 176..193; Low complexity; 234..250; Low complexity; 363..375; Basic and acidic residues
Motif
268..276; Nuclear localization signal
Region
85..253; Disordered; 336..398; Disordered
Protein Families
FAM53 family
Sequence Similarities
Belongs to the FAM53 family.
Clinical Relevance