Protein detail

GAG2A

G antigen 2A (GAGE-2A)

Entry name
GAG2A
UniProt ID
EVMP confidence score
0.38
Supporting publications (n)
2
Transmembrane count
Protein classification
Predicted intracellular proteins
EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information11
Protein Names
G antigen 2A (GAGE-2A)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Entrez Gene Symbol
Gene Synonym (2)
CT4.2GAGE2
Gene Description
G antigen 2A
Chromosome
X
Position
49589496-49596824
Supporting publications (n)
2
EVMP confidence score
0.38
Fluorescence & Localization3
Tissue SpecificlungCell SpecificBrain excitatory neuronsSingle-Nuclei Brain Specificendothelial cell
Function & Pathway6
Protein Function
Predicted intracellular proteins
Canonical Pathways
M53 Pid integrin3 pathway
Mediation Categories
Other mediation
Relations & Evidence1

Isolation & Detection Technology (1)

1 record.

EV Isolation MethodDetection MethodNumber of ReferencesReferences
Differential UltracentrifugationR SequencingMass spectrometry139329301
Sequence, Structure & Domains7

Sequences

Length
116
Mass
12,785
Sequence
MSWRGRSTYRPRPRRYVEPPEMIGPMRPEQFSDEVEPATPEEGEPATQRQDPAAAQEGQDEGASAGQGPKPEAHSQEQGHPQTGCECEDGPDGQEMDPPNPEEVKTPEEGEKQSQC

Domain & Motif Annotations

Compositional Bias
31..44; Acidic residues; 86..95; Acidic residues; 102..116; Basic and acidic residues
Region
1..116; Disordered
Protein Families
GAGE family
Sequence Similarities
Belongs to the GAGE family.
Clinical Relevance1
Antibody
Supporting Publications2
PMIDTitleAbstract
26775013Proteomic characterization of circulating extracellular vesicles identifies novel serum myeloma associated markers.No abstract available
40098346Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays.No abstract available