Protein detail
MRNIP
MRN complex-interacting protein (MRN-interacting protein)
Entry name MRNIP | UniProt ID | EVMP score 0.38 |
Frequency 4 | Transmembrane count | Protein classification Predicted intracellular proteins |
EVMP score: annotation confidence score.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Basic Information
Protein Names
MRN complex-interacting protein (MRN-interacting protein)
Protein Class
Predicted intracellular proteins
Protein Function
Predicted intracellular proteins
Ensembl
Entrez Gene Symbol
Gene Synonym
C5orf45DKFZp686L2452LOC51149MGC65027MGC78537
Gene Description
MRN complex interacting protein
Chromosome
5
Position
179835133-179862173
Frequency
4
EVMP Score
0.38
Fluorescence & Localization
Tissue SpecificbrainCell SpecificExtravillous trophoblastsSingle-Nuclei Brain Specificdeep-layer near-projecting
Function & Pathway
Protein Function
Predicted intracellular proteins
Cellular Component
Molecular Function
Biological Process
Mediation Categories
Other mediation
Relations & Evidence
Enzyme-Mediated Modification
0 records.
Ligand-Receptor Signaling
4 records.
| Category | Parent | Database | Transmitter | Receiver | Secreted | Plasma Membrane (Transmembrane) | Plasma Membrane (Peripheral) |
|---|---|---|---|---|---|---|---|
| intracellular | intracellular | ComPPI | No | No | No | No | No |
| intracellular | intracellular | GO_Intercell | No | No | No | No | No |
| intracellular | intracellular | UniProt_location | No | No | No | No | No |
| intracellular | intracellular | OmniPath | No | No | No | No | No |
Regulatory Interaction Network
0 records.
Protein Complex Composition
0 records.
Isolation & Detection Technology
1 record.
| EV Isolation Method | Detection Method | Number of References | References |
|---|---|---|---|
| Mass spectrometry | 0 |
Sequence, Structure & Domains
Sequences
Length
343
Mass
37,743
Sequence
MASLQRSRVLRCCSCRLFQAHQVKKSVKWTCKACGEKQSFLQAYGEGSGADCRRHVQKLNLLQGQVSELPLRSLEETVSASEEENVGHQQAGNVKQQEKSQPSESRWLKYLEKDSQELELEGTGVCFSKQPSSKMEEPGPRFSQDLPRKRKWSRSTVQPPCSRGVQDSGGSEVAWGPQKGQAGLTWKVKQGSSPCLQENSADCSAGELRGPGKELWSPIQQVTATSSKWAQFVLPPRKSSHVDSEQPRSLQRDPRPAGPAQAKQGTPRAQASREGLSRPTAAVQLPRATHPVTSGSERPCGKTSWDARTPWAEGGPLVLEAQNPRPTRLCDLFITGEDFDDDV
Alternative Products
Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q6NTE8-1; Sequence=Displayed; Name=2; IsoId=Q6NTE8-2; Sequence=VSP_032560, VSP_032561, VSP_032562; Name=3; IsoId=Q6NTE8-3; Sequence=VSP_047227
Alternative Sequence
1..42; MASLQRSRVLRCCSCRLFQAHQVKKSVKWTCKACGEKQSFLQ -> MQSARAWLPGDCTSRDGVASAFSGATLLQLPPLPGAPGKKECQVDMQSLWREAVLFAEFPRHGAPASELPVPSGSEMDGAESGK (in isoform 2); 43..97; Missing (in isoform 3); 222..229; VTATSSKW -> DGYKEILF (in isoform 2); 230..343; Missing (in isoform 2)
3D Structural Models
Domain & Motif Annotations
Compositional Bias
87..104; Polar residues; 193..202; Polar residues; 240..255; Basic and acidic residues
Motif
148..151; Nuclear localization signal (NLS)
Region
75..104; Disordered; 128..178; Disordered; 193..212; Disordered; 213..237; Necessary for the association with the MRN complex; 230..324; Disordered
Protein Families
MRNIP family
Sequence Similarities
Belongs to the MRNIP family.
Clinical Relevance
Antibody